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Anti-DPYD Antibody (3L947)

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Catalog No. TMAB-05308

Anti-DPYD Antibody (3L947) is a Rabbit antibody targeting DPYD. Anti-DPYD Antibody (3L947) can be used in IF, IHC-Fr, IHC-P.

Anti-DPYD Antibody (3L947)

Anti-DPYD Antibody (3L947)

Copy Product Info
😃Good
Catalog No. TMAB-05308
Anti-DPYD Antibody (3L947) is a Rabbit antibody targeting DPYD. Anti-DPYD Antibody (3L947) can be used in IF, IHC-Fr, IHC-P.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1517-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4727-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-DPYD Antibody (3L947) is a Rabbit antibody targeting DPYD. Anti-DPYD Antibody (3L947) can be used in IF, IHC-Fr, IHC-P.
Ig Type
IgG
Clone
3L947
Reactivity
Human
Verified Activity
1. Western blot analysis of HeLa cell lysate. Using DPYD (TMAB-05308) monoclonal antibody at 1: 1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
2. Paraformaldehyde-fixed, paraffin embedded Human Liver Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with DPYD Monoclonal Antibody, Unconjugated (TMAB-05308) at 1:200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L-HRP and DAB staining.
3. Paraformaldehyde-fixed, paraffin embedded Human Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with DPYD Monoclonal Antibody, Unconjugated (TMAB-05308) at 1:200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L-HRP and DAB staining.
4. Paraformaldehyde-fixed, paraffin embedded Human Colon; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with DPYD Monoclonal Antibody, Unconjugated (TMAB-05308) at 1:200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L-HRP and DAB staining.
5. Paraformaldehyde-fixed, paraffin embedded Human Small Intestine; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with DPYD Monoclonal Antibody, Unconjugated (TMAB-05308) at 1:200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L-HRP and DAB staining.
Application
Recommended Dose
IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm
Tissue SpecificityFound in most tissues with greatest activity found in liver and peripheral blood mononuclear cells.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundInvolved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil.
Antigen Details
Immunogen
A synthesized peptide: human DHPDHase
Antigen Species
Human
Gene Name
DPYD
Gene ID
Protein Name
Dihydropyrimidine dehydrogenase [NADP(+)]
Uniprot ID
Function
Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil.
Chemical Properties
Molecular WeightTheoretical: 111 kDa. Actual: 110 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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