TGF alpha Protein, Human, Recombinant V2

Name: TGF alpha Protein, Human, Recombinant V2
Brand: TargetMol
SKU: TMPY-03958U
Rating: 4.5 (1 reviews)

(Synonyms: transforming growth factor α, transforming growth factor alpha, TGF-α, TGFa, TFGA) Copy Product Info

Synonyms: transforming growth factor α, transforming growth factor alpha, TGF-α, TGFa, TFGA

Catalog No. TMPY-03958U Copy Product Info

TGF alpha Protein, Human, Recombinant V2 is expressed in E. coli. The accession number is P01135.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$64	7-10 days	7-10 days
10 µg	$98	7-10 days	7-10 days
20 µg	$165	7-10 days	7-10 days
50 µg	$295	7-10 days	7-10 days
100 µg	$462	7-10 days	7-10 days
200 µg	$791	7-10 days	7-10 days
500 µg	$1,680	7-10 days	7-10 days
1 mg	$3,000	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	ED 50 < 0.2 ng/ml, measured by Cell Proliferation Assay using BALB/c 3T3 cells, corresponding to a specific activity of ≥ 5.0 × 10^6 units/mg.
Description	TGF alpha Protein, Human, Recombinant V2 is expressed in E. coli. The accession number is P01135.
Species	Human
Expression System	E. coli
Tag	Tag Free
Accession Number	P01135
Construction	Val40-Ala89
Protein Purity	> 95% as determined by SDS-PAGE
Endotoxin	< 0.2 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	transforming growth factor α, transforming growth factor alpha, TGF-α, TGFa, TFGA
Research Background	Transforming Growth Factor-alpha (TGF-α) , also known as sarcoma growth factor, TGF-type I and ETGF, is a member of the EGF family of cytokines. It is expressed in monocytes, brain cells, keratinocytes and various tumor cells. TGF-α signals through EGFR and acts synergistically with TGF-beta to promote the proliferation of a wide range of epidermal and epithelial cells. TGF-α is a transforming growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. The biological actions of TGF-α and EGF are similar. For instance, TGF-α and EGF bind to the same receptor. When TGF-α binds to EGFR it can initiate multiple cell proliferation events.

Chemical Properties

Molecular Weight

5.8 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.