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Anti-TSHR Antibody (8N430) is an antibody targeting TSHR. Anti-TSHR Antibody (8N430) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $209 | 7-10 days | |
100 μL | $348 | 7-10 days |
Description | Anti-TSHR Antibody (8N430) is an antibody targeting TSHR. Anti-TSHR Antibody (8N430) can be used in ELISA. |
Ig Type | hIgG1 |
Clone | 8N430 |
Reactivity | Human |
Verified Activity | 1. The Binding Activity of Human TSHR with Anti-TSHR Recombinant Antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Human TSHR at 10 μg/mL can bind Anti-TSHR recombinant antibody. The EC50 is 30.81-36.12 ng/mL.The VLPs is negative control. 2. Untransfected HEK293T cells (green line) and transfected Human TSHR HEK293T stable cells (red line) were stained with anti-TSHR antibody (TMAH-01217) (2µg/1*10^6 cells), washed and then followed by APC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry. 3. The purity of TSHR was greater than 95% as determined by SEC-HPLC |
Application | ELISA |
Recommended Dose | ELISA:1:5000-1:50000. |
Antibody Type | Monoclonal |
Subcellular Localization | Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
Research Background | Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein: Human TSHR Protein |
Antigen Species | Human |
Gene ID | 7253 |
Uniprot ID | |
Biology Area | Neuroscience, Signal transduction |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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