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Anti-FTCD Antibody (8U835) (Synonyms: LCHC1, formimidoyltransferase cyclodeaminase)

Catalog No. TMAC-00031 Copy Product Info
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Anti-FTCD Antibody (8U835) is a Rabbit antibody targeting FTCD. Anti-FTCD Antibody (8U835) can be used in FCM,IHC,WB.

Anti-FTCD Antibody (8U835)

Copy Product Info
🥰Excellent
Catalog No. TMAC-00031
Synonyms LCHC1, formimidoyltransferase cyclodeaminase

Anti-FTCD Antibody (8U835) is a Rabbit antibody targeting FTCD. Anti-FTCD Antibody (8U835) can be used in FCM,IHC,WB.

Anti-FTCD Antibody
(8U835)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2967-10 days7-10 days
100 μL$4987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-FTCD Antibody (8U835) is a Rabbit antibody targeting FTCD. Anti-FTCD Antibody (8U835) can be used in FCM,IHC,WB.
SynonymsLCHC1, formimidoyltransferase cyclodeaminase
Ig Type
IgG
Clone
8U835
Reactivity
Human
Verified Activity
1. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-58K Golgi protein antibody. Counter stained with hematoxylin.
2. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-58K Golgi protein antibody. Counter stained with hematoxylin.
3. Flow cytometric analysis of HepG2 cells with 58K Golgi protein antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
verifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research Background58K protein antibodies are excellent for use as markers for the Golgi complex. The 58K protein has been identified as being FTCD, a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Defects in FTCD are the cause of glutamate formiminotransferase deficiency [also known as formiminoglutamicaciduria (FIGLU-uria)], an autosomal recessive disorder. Features of a severe phenotype include elevated levels of formiminoglutamate (FIGLU) in the urine in response to histidine administration, megaloblastic anemia and mental retardation. Features of a mild phenotype include high urinary excretion of FIGLU in the absence of histidine administration, mild developmental delay and no hematological abnormalities.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 59 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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