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Anti-Calsequestrin Antibody (6K102)

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Catalog No. TMAB-03584 Copy Product Info
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Anti-Calsequestrin Antibody (6K102) is a Rabbit antibody targeting Calsequestrin. Anti-Calsequestrin Antibody (6K102) can be used in IHC-P,IHC-Fr,FCM,IF.
Anti-Calsequestrin Antibody
(6K102)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1497-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Calsequestrin Antibody (6K102) is a Rabbit antibody targeting Calsequestrin. Anti-Calsequestrin Antibody (6K102) can be used in IHC-P,IHC-Fr,FCM,IF.
Ig Type
IgG
Clone
6K102
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
IHC-P: 1:50-200; IHC-Fr: 1:50-200; FCM: 1:50-100; IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationSarcoplasmic reticulum lumen. Mitochondrion. Note=This isoform of calsequestrin occurs in the sarcoplasmic reticulum's terminal cisternae luminal spaces of fast skeletal muscle cells. Also mitochondrial according to PubMed:7945294.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundCalsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. The release of calcium bound to calsequestrin through a calcium release channel triggers muscle contraction. Binds 40 to 50 moles of calcium. Also binds laminin.
Antigen Details
Immunogen
A synthesized peptide: human Calsequestrin 1
Antigen Species
Human
Gene Name
CASQ1
Gene ID
Protein Name
Calsequestrin-1
Uniprot ID
Function
Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. The release of calcium bound to calsequestrin through a calcium release channel triggers muscle contraction. The skeletal muscle isoform (CASQ1) binds around 80 Ca(2+) ions, while the cardiac isoform (CASQ2) binds approximately 60 Ca(2+).
Chemical Properties
Molecular WeightTheoretical: 45 kDa. Actual: 60 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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