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Anti-UBE2D1 Antibody (8X135)

Catalog No. TMAB-13929 Copy Product Info
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Anti-UBE2D1 Antibody (8X135) is a Rabbit antibody targeting UBE2D1. Anti-UBE2D1 Antibody (8X135) can be used in WB,IHC-P,IHC-Fr,IP,IF.

Anti-UBE2D1 Antibody (8X135)

Copy Product Info
🥰Excellent
Catalog No. TMAB-13929

Anti-UBE2D1 Antibody (8X135) is a Rabbit antibody targeting UBE2D1. Anti-UBE2D1 Antibody (8X135) can be used in WB,IHC-P,IHC-Fr,IP,IF.

Anti-UBE2D1 Antibody
(8X135)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1507-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4717-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-UBE2D1 Antibody (8X135) is a Rabbit antibody targeting UBE2D1. Anti-UBE2D1 Antibody (8X135) can be used in WB,IHC-P,IHC-Fr,IP,IF.
Ig Type
IgG
Clone
8X135
Reactivity
Human,Mouse,Rat
Verified Activity
25 ug total protein per lane of various lysates (see on figure) probed with UBE2D1 monoclonal antibody, unconjugated (TMAB-13929) at 1: 1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; IP: 1:20-50; IF: 1:100-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm.
Tissue SpecificityUbiquitous. Up-regulated in livers of iron-overloaded patients with hereditary hemochromatosis.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundAccepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-linked polyubiquitination. Involved in the selective degradation of short-lived and abnormal proteins. Down-regulated during the S-phase it is involved in progression through the cell cycle.
Antigen Details
Immunogen
A synthesized peptide: human UBE2D1
Antigen Species
Human
Gene Name
UBE2D1
Gene ID
Protein Name
Ubiquitin-conjugating enzyme E2 D1
Uniprot ID
Function
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of STUB1, TRAF6 and TRIM63/MURF1. Ubiquitinates STUB1-associated HSP90AB1 in vitro. Lacks inherent specificity for any particular lysine residue of ubiquitin. Essential for viral activation of IRF3. Mediates polyubiquitination of CYP3A4.
Chemical Properties
Molecular WeightTheoretical: 17 kDa. Actual: 17 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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