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Basiliximab

(Synonyms: CHI 621) Copy Product Info
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Synonyms: CHI 621

Catalog No. T73698 Copy Product Info
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Basiliximab (CHI 621) is a chimeric mouse/human IgG1 monoclonal recombinant antibody targeting the interleukin-2 receptor, demonstrating potent immunosuppressive activity for use in kidney transplantation studies.
Basiliximab
Cas No. 179045-86-4
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$228In StockIn Stock
5 mg$745In StockIn Stock
10 mg$1,180-In Stock
25 mg$1,780-In Stock
50 mg$2,380-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:94.1% (SDS-PAGE); 95.3% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Basiliximab (CHI 621) is a chimeric mouse/human IgG1 monoclonal recombinant antibody targeting the interleukin-2 receptor, demonstrating potent immunosuppressive activity for use in kidney transplantation studies.
In vitro
Specifically inhibiting T lymphocyte proliferation, Basiliximab binds to IL-2Rα[1]. It binds only to activated lymphocytes and macrophages/monocytes[3]. Basiliximab does not affect resting T lymphocytes that do not express IL-2Rα[2].
Endotoxin<1.0 EU/mg
SynonymsCHI 621
Reactivity
Human
Verified Activity
Immobilized Human CD25/IL2R Protein (His) (TMPY-01103) at 1 μg/mL (100 μL/well) can bind Basiliximab. The EC50 is 3.33 ng/mL.
Basiliximab
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetIL-2Ra/CD25
Chemical Properties
Molecular Weight144.01 kDa
Cas No.179045-86-4
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
StorageStore at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: Basiliximab chemical structure | Basiliximab in vitro | Basiliximab molecular weight