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Anti-PRDX2 Antibody (4H768) is a Mouse antibody targeting PRDX2. Anti-PRDX2 Antibody (4H768) can be used in WB,ICC/IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
| Description | Anti-PRDX2 Antibody (4H768) is a Mouse antibody targeting PRDX2. Anti-PRDX2 Antibody (4H768) can be used in WB,ICC/IF. |
| Ig Type | IgG1, Kappa |
| Clone | 4H768 |
| Reactivity | Human,Mouse |
| Verified Activity | 1. Cell line: MCF-7 Fixative: 4% Paraformaldehyde Permeabilization: 0.1% TritonX-100 Primary ab dilution: 1:50 Primary incubation condition: 4°C overnight Secondary ab: Goat Anti-Mouse IgG Nuclear counter stain: DAPI (Blue) Comment: Color green is the positive signal for TMAB-11721 2. Sample: Lane 1: Mouse NIH/3T3 cell lysates Lane 2: Mouse Testis tissue lysates Lane 3: Mouse Heart tissue lysates Lane 4: Mouse Cerebrum tissue lysates Lane 5: Human Raji cell lysates Lane 6: Human MCF-7 cell lysates Lane 7: Human HeLa cell lysates Lane 8: Human 293T cell lysates Lane 9: Human MDA-MB-231 cell lysates Lane 10: Human HepG2 cell lysates Primary: Anti-PRDX2 (TMAB-11721) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: kDa Observed band size: 20 kDa |
| Application | |
| Recommended Dose | WB: 1:500-1000; ICC/IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Cytoplasm. |
| Construction | Recombinant Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13. [provided by RefSeq, Mar 2013] |
| Gene Name | PRDX2 |
| Gene ID | |
| Protein Name | Peroxiredoxin-2 |
| Function | Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system. It is not able to receive electrons from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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