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Anti-K63-linkage Specific Ubiquitin Antibody (7M837)

(Synonyms: UBB, Polyubiquitin-B) Copy Product Info
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Synonyms: UBB, Polyubiquitin-B

Catalog No. TMAC-02295 Copy Product Info
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Anti-K63-linkage Specific Ubiquitin Antibody (7M837) is a Rabbit antibody targeting K63-linkage Specific Ubiquitin. Anti-K63-linkage Specific Ubiquitin Antibody (7M837) can be used in ICC/IF,IHC,WB.
Anti-K63-linkage Specific Ubiquitin Antibody
(7M837)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4967-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-K63-linkage Specific Ubiquitin Antibody (7M837) is a Rabbit antibody targeting K63-linkage Specific Ubiquitin. Anti-K63-linkage Specific Ubiquitin Antibody (7M837) can be used in ICC/IF,IHC,WB.
SynonymsUBB, Polyubiquitin-B
Ig Type
IgG
Clone
7M837
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:1000; IHC: 1:50-200; ICC/IF: 1:100-500
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundUbiquitin (Ub) is among the most phylogenetically conserved proteins known. The primary function of ubiquitin is to clear abnormal, foreign and improperly folded proteins by targeting them for degradation by the 26S Proteosome. This small, 76 amino acid protein can be covalently attached to cellular proteins via an isopeptide linkage between the carboxy terminal group of ubiquitin and lysine amino groups on the acceptor protein. For proteolysis to occur, ubiquitin oligomers must be assembled. Ubiquitin chains on proteolytic substrates are commonly found to have an isopeptide bridge between Lys 48 of one ubiquitin molecule and the carboxy-terminus of a neighboring ubiquitin molecule. Ubiquitin also plays a role in regulating signal transduction cascades through the elimination inhibitory proteins, such as IκB-α and p27.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 60-100 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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