CD155/PVR Protein, Human, Recombinant (hFc) V2

Catalog No. TMPY-00699U

CD155/PVR Protein, Human, Recombinant (hFc) V2 is expressed in HEK293 Cells. The accession number is P15151-1.

CD155/PVR Protein, Human, Recombinant (hFc) V2

Catalog No. TMPY-00699U

CD155/PVR Protein, Human, Recombinant (hFc) V2 is expressed in HEK293 Cells. The accession number is P15151-1.

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Product Information

Biological Activity	Immobilized Human CD96, mFc Tag at 5 μg/ml (100 μl/Well) on the plate. Dose response curve for Human CD155, hFc Tag with the EC50 of 0.21 μg/ml determined by ELISA. Human CD155, hFc Tag captured on CM5 Chip via Protein A can bind Human CD96, His Tag with an affinity constant of 0.958 μM as determined in SPR assay (Biacore T200).
Description	CD155/PVR Protein, Human, Recombinant (hFc) V2 is expressed in HEK293 Cells. The accession number is P15151-1.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	P15151-1
Synonyms	TAGE4,PVS,poliovirus receptor,Necl-5,NECL5,HVED,CD155
Construction	Trp21-Asn343
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by SEC-HPLC
Molecular Weight	61.8 kDa (Predicted); 75-100 kDa (Due to glycosylation)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background	CD155 is a cell surface adhesion molecule functioning in tumor cell migration, invasion, and metastasis, and not surprisingly, is also designated as a common tumor-associated antigen. CD155 is also recognized by NK cells to induce their cytotoxicity. CD155 is also commonly referred to as the "poliovirus receptor," or PVR.