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RAGE Protein, Human, Recombinant (His) V2

TargetMol | SPR
Catalog No. TMPY-02927U

RAGE Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is Q15109-1.

RAGE Protein, Human, Recombinant (His) V2

RAGE Protein, Human, Recombinant (His) V2

TargetMol | SPR
Catalog No. TMPY-02927U
RAGE Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is Q15109-1.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 μg$487-10 days7-10 days
10 μg$757-10 days7-10 days
20 μg$1187-10 days7-10 days
50 μg$2297-10 days7-10 days
100 μg$3867-10 days7-10 days
200 μg$6827-10 days7-10 days
500 μg$1,4307-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse [1-2 days] Global Warehouse [5-7 days]
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Product Information

Biological Activity
Human AGER, His Tag immobilized on CM5 Chip can bind Human HMGB1, His Tag with an affinity constant of 0.19 μM as determined in SPR assay (Biacore T200).
Description
RAGE Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is Q15109-1.
Species
Human
Expression System
HEK293 Cells
TagC-His
Accession NumberQ15109-1
Synonyms
RAGE,AGER,advanced glycosylation end product-specific receptor
Construction
Ala23- Ala344
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight35.3 kDa (Predicted); 50-60 kDa (Due to glycosylation)
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Stability & Storage
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background
The receptor for advanced glycation end products (AGER) is an oncogenic transmembranous receptor up-regulated in various human cancers. AGER promotes proliferation, migration, and inhibits apoptosis of squamous cervical cancer and might function as a tumor promoter in cervical cancer. Our study provides novel evidence for a potential role of AGER in bridging human papillomavirus (HPV)-induced inflammation and cervical cancer.

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