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Anti-GluR2 Antibody (6P901)
🥰Excellent
Catalog No. TMAB-06544
Antibody Type: Recombinant Rabbit Monoclonal
Application: WB,ICC/IF,IP
Reactivity: Mouse,Rat (predicted:Human)
Anti-GluR2 Antibody (6P901)
Anti-GluR2 Antibody (6P901)
🥰Excellent
Catalog No. TMAB-06544
Antibody Type: Recombinant Rabbit Monoclonal
Application: WB,ICC/IF,IP
Reactivity: Mouse,Rat (predicted:Human)
Application: WB,ICC/IF,IP
Reactivity: Mouse,Rat (predicted:Human)
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-GluR2 Antibody (6P901) is a Rabbit antibody targeting GluR2. Anti-GluR2 Antibody (6P901) can be used in WB,ICC/IF,IP. |
| Ig Type | IgG |
| Clone | 6P901 |
| Reactivity | Mouse,Rat (predicted:Human) |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC/IF: 1:50-200; IP: 1:20-50 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | GluR2 an integral membrane protein belonging to the glutamate-gated ion channel family. L-glutamate (Glu) acts as an excitatory neurotransmitter at many synapses in the central nervous system. Glutamate receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. |
| Immunogen | A synthesized peptide: human GluR2 |
| Antigen Species | Human |
| Gene Name | GRIA2 |
| Gene ID | |
| Protein Name | Glutamate receptor 2 |
| Uniprot ID | |
| Function | Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. |
| Molecular Weight | Theoretical: 99 kDa. Actual: 98 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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