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Synonyms: TMPY-01815, Ovarian tumor-associated antigen MOv18, MOv18, KB cells FBP, FR-α, FR-alpha, FR α, FR alpha, FR a, FOLR-1, FOLR1, FOLR 1, FOLR, Folbp1, Folate receptor α, Folate receptor alpha, folate receptor 1 (adult), folate receptor 1, Folate receptor 1, Folate receptor, Folate Binding Protein, Fbp1, FBP, Adult folate-binding protein, adult


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 µg | $189 | 7-10 days | 7-10 days | |
| 20 µg | $293 | 7-10 days | 7-10 days | |
| 50 µg | $548 | 7-10 days | 7-10 days | |
| 100 µg | $873 | 7-10 days | 7-10 days | |
| 200 µg | $1,390 | 7-10 days | 7-10 days | |
| 500 µg | $2,580 | 7-10 days | 7-10 days |
| Bioactivity | Immobilized FITC-Labeled Human FOLR1, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-FOLR1 Antibody, hFc Tag with the EC50 of 15.0 ng/ml determined by ELISA. |
| Description | FOLR1 Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 Cells. The accession number is P15328. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His-Avi |
| Accession Number | P15328 |
| Construction | Arg25-Met233 |
| Protein Purity | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
| Formulation | Supplied as 0.22 μm filtered solution in PBS (pH 7.4). |
| Synonyms | TMPY-01815, Ovarian tumor-associated antigen MOv18, MOv18, KB cells FBP, FR-α, FR-alpha, FR α, FR alpha, FR a, FOLR-1, FOLR1, FOLR 1, FOLR, Folbp1, Folate receptor α, Folate receptor alpha, folate receptor 1 (adult), folate receptor 1, Folate receptor 1, Folate receptor, Folate Binding Protein, Fbp1, FBP, Adult folate-binding protein, adult |
| Research Background | Folate Receptor 1 (FOLR1), also known as Folate Receptor alpha and Folate Binding Protein (FBP), is a 37 - 42 kDa protein that mediates the cellular uptake of folic acid and reduced folates. Dietary folates are required for many key metabolic processes including nucleotide and methionine synthesis, the interconversion of glycine and serine, and histidine breakdown. FOLR1 binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. |
| Molecular Weight | 27.5 kDa (Predicted); 37-47 kDa (Reducing condition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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