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Anti-HMGCS2 Antibody (2I93) (Synonyms: mitochondrial, Hydroxymethylglutaryl-CoA synthase, HMGCS 2, HMG-CoA sy...)

Catalog No. TMAH-00561 Copy Product Info
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Anti-HMGCS2 Antibody (2I93) is an antibody targeting HMGCS2. Anti-HMGCS2 Antibody (2I93) can be used in ELISA,IHC,WB.

Anti-HMGCS2 Antibody (2I93)

Copy Product Info
🥰Excellent
Catalog No. TMAH-00561
Synonyms mitochondrial, Hydroxymethylglutaryl-CoA synthase, HMGCS 2, HMG-CoA synthase, EC 2.3.3.10, 3-hydroxy-3-methylglutaryl coenzyme A synthase

Anti-HMGCS2 Antibody (2I93) is an antibody targeting HMGCS2. Anti-HMGCS2 Antibody (2I93) can be used in ELISA,IHC,WB.

Anti-HMGCS2 Antibody
(2I93)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2097-10 days7-10 days
100 μL$3477-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Anti-HMGCS2 Antibody (2I93) is an antibody targeting HMGCS2. Anti-HMGCS2 Antibody (2I93) can be used in ELISA,IHC,WB.
Synonymsmitochondrial, Hydroxymethylglutaryl-CoA synthase, HMGCS 2, HMG-CoA synthase, EC 2.3.3.10, 3-hydroxy-3-methylglutaryl coenzyme A synthase
Ig Type
Rabbit IgG
Clone
2I93
Reactivity
Human
Verified Activity
1. Western Blot
-Positive WB detected in: A549 whole cell lysate, Ntera-2 whole cell lysate
-All lanes: HMGCS2 antibody at 1:500
-Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution
-Predicted band size: 57, 53, 51 kDa
-Observed band size: 55 kDa
2. IHC image of TMAH-00561 diluted at 1:100 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.
3. IHC image of TMAH-00561 diluted at 1:100 and staining in paraffin-embedded human appendix tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.
Application
Recommended Dose
WB:1:500-1:2000; IHC:1:50-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationMitochondrion.
Tissue SpecificityExpression in liver is 200-fold higher than in any other tissue. Low expression in colon, kidney, testis, and pancreas. Very low expression in heart and skeletal muscle. Not detected in brain.; [Isoform 3]: Highest expression detected in heart and skeleta
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundCatalyzes the first irreversible step in ketogenesis, condensing acetyl-CoA to acetoacetyl-CoA to form HMG-CoA, which is converted by HMG-CoA reductase (HMGCR) into mevalonate.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human HMGCS2
Antigen Species
Human
Gene Name
HMGCS2
Gene ID
Uniprot ID
Biology Area
Cancer, Cardiovascular, Metabolism, Signal transduction
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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