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Anti-SLC6A4 Antibody (8M887) is an antibody targeting SLC6A4. Anti-SLC6A4 Antibody (8M887) can be used in ELISA,IHC,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $208 | 7-10 days | 7-10 days | |
| 100 μL | $349 | 7-10 days | 7-10 days |
| Description | Anti-SLC6A4 Antibody (8M887) is an antibody targeting SLC6A4. Anti-SLC6A4 Antibody (8M887) can be used in ELISA,IHC,WB. |
| Synonyms | Solute carrier family 6 member 4, Sodium-dependent serotonin transporter, SERT, HTT, 5HTT, 5HT transporter |
| Ig Type | Rabbit IgG |
| Clone | 8M887 |
| Reactivity | Human |
| Verified Activity | 1. Western Blot -Positive WB detected in: U-87 whole cell lysate, 293T whole cell lysate, U-251 whole cell lysate, HepG2 whole cell lysate -All lanes: Serotonin transporter antibody at 1:1000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 71, 75 kDa -Observed band size: 55 kDa 2. IHC image of TMAH-01107 diluted at 1:100 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
| Application | |
| Recommended Dose | WB:1:500-1:5000; IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. Endomembrane system; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Cell junction, synapse. Cell junction, focal adhesion. |
| Tissue Specificity | Expressed in platelets (at protein level). |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human Serotonin transporter |
| Antigen Species | Human |
| Gene Name | SLC6A4 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Neuroscience, Metabolism, Signal transduction |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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