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Anti-Thioredoxin Antibody (4X610)
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Catalog No. TMAB-13511
Anti-Thioredoxin Antibody (4X610) is a Rabbit antibody targeting Thioredoxin. Anti-Thioredoxin Antibody (4X610) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP.
Anti-Thioredoxin Antibody (4X610)
Anti-Thioredoxin Antibody (4X610)
😃Good
Catalog No. TMAB-13511
Anti-Thioredoxin Antibody (4X610) is a Rabbit antibody targeting Thioredoxin. Anti-Thioredoxin Antibody (4X610) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $264 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Thioredoxin Antibody (4X610) is a Rabbit antibody targeting Thioredoxin. Anti-Thioredoxin Antibody (4X610) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP. |
| Ig Type | IgG |
| Clone | 4X610 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200; IP: 1:20-50 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Cytoplasm. Secreted. Note=Secreted by a leaderless secretory pathway. Predominantly in the cytoplasm in non irradiated cells. Radiation induces translocation of TRX from the cytoplasm to the nucleus. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. |
| Immunogen | A synthesized peptide: human Thioredoxin |
| Antigen Species | Human |
| Gene Name | TXN |
| Gene ID | |
| Protein Name | Thioredoxin |
| Uniprot ID | |
| Function | Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. |
| Molecular Weight | Theoretical: 12 kDa. Actual: 12 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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