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Synonyms: tumor necrosis factor receptor superfamily member 1A, TNF-R-I, TNFR60, TNF-R55, TNFR55, TNFR1-d2, TNFR1, TNF-R, TNFAR, TBP1, p60, p55-R, p55, MS5, FPF, CD120a


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $36 | 7-10 days | 7-10 days | |
| 10 µg | $53 | 7-10 days | 7-10 days | |
| 20 µg | $84 | 7-10 days | 7-10 days | |
| 50 µg | $159 | 7-10 days | 7-10 days | |
| 100 µg | $263 | 7-10 days | 7-10 days | |
| 200 µg | $466 | 7-10 days | 7-10 days | |
| 500 µg | $986 | 7-10 days | 7-10 days |
| Bioactivity | Immobilized Human TNFR1, His Tag at 0.5 μg/ml (100 μl/Well). Dose response curve for Biotinylated Human TNF alpha, His Tag with the EC50 of 16.5 ng/ml determined by ELISA. |
| Description | TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P19438-1. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | P19438-1 |
| Construction | Leu30-Thr211 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | tumor necrosis factor receptor superfamily member 1A, TNF-R-I, TNFR60, TNF-R55, TNFR55, TNFR1-d2, TNFR1, TNF-R, TNFAR, TBP1, p60, p55-R, p55, MS5, FPF, CD120a |
| Research Background | Tumour necrosis factor alpha (TNF-α) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2. In the setting of acute injury, selective inhibition of TNFR1 is predicted to attenuate the cell death and inflammation associated with TNF-α, while sparing or potentiating the protective effects of TNFR2 signalling. |
| Molecular Weight | 23.3 kDa (Predicted); 38-48 kDa (Due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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