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Anti-Scramblase 1 Antibody (3N29)
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Catalog No. TMAB-12596
Anti-Scramblase 1 Antibody (3N29) is a Rabbit antibody targeting Scramblase 1. Anti-Scramblase 1 Antibody (3N29) can be used in WB,ICC/IF,IP,FCM.
Anti-Scramblase 1 Antibody (3N29)
Anti-Scramblase 1 Antibody (3N29)
😃Good
Catalog No. TMAB-12596
Anti-Scramblase 1 Antibody (3N29) is a Rabbit antibody targeting Scramblase 1. Anti-Scramblase 1 Antibody (3N29) can be used in WB,ICC/IF,IP,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Scramblase 1 Antibody (3N29) is a Rabbit antibody targeting Scramblase 1. Anti-Scramblase 1 Antibody (3N29) can be used in WB,ICC/IF,IP,FCM. |
| Ig Type | IgG |
| Clone | 3N29 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC/IF: 1:50-200; IP: 1:20-50; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane. |
| Tissue Specificity | Expressed in platelets, erythrocyte membranes, lymphocytes, spleen, thymus, prostate, testis, uterus, intestine, colon, heart, placenta, lung, liver, kidney and pancreas. Not detected in brain and skeletal muscle. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Catalyzes calcium-induced ATP-independent rapid bidirectional and non-specific movement of phospholipids (lipid scrambling or lipid flip-flop) between the inner and outer leaflet of the plasma membrane resulting in collapse of the phospholipid asymmetry which leads to phosphatidylserine externalization on the cell surface. |
| Immunogen | A synthesized peptide: human Phospholipid scramblase 1 |
| Antigen Species | Human |
| Gene Name | PLSCR1 |
| Gene ID | |
| Protein Name | phospholipid scramblase 1 |
| Uniprot ID | |
| Function | May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.
May play a role in the antiviral response of interferon (IFN) by amplifying and enhancing the IFN response through increased expression of select subset of potent antiviral genes. May contribute to cytokine-regulated cell proliferation and differentiation. |
| Molecular Weight | Theoretical: 35 kDa. Actual: 35 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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