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Anti-Claudin-18 Antibody (5M288) is an antibody targeting Claudin-18. Anti-Claudin-18 Antibody (5M288) can be used in ELISA,FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $208 | 7-10 days | |
100 μL | $347 | 7-10 days |
Description | Anti-Claudin-18 Antibody (5M288) is an antibody targeting Claudin-18. Anti-Claudin-18 Antibody (5M288) can be used in ELISA,FCM. |
Synonyms | SFTPJ, SFTA5, CLDN18, CLDN 18, claudin 18 |
Ig Type | Human IgG1 |
Clone | 5M288 |
Reactivity | Human |
Verified Activity | 1. Untransfected KATO3 cells surface (green line), transfected Human CLDN18.2 KATO3 stable cells surface (red line) and transfected Human CLDN18.1 NIH-3T3 stable cells surface (blue line) were stained with anti-CLDN18.2 antibody (2µg/1*10^6 cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry. 2. The Binding Activity of Human CLDN18.2 with Anti-CLDN18 recombinant antibody. Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CLDN18.2 at 5 μg/mL can bind Anti-CLDN18 recombinant antibody, the EC50 is 2.947-8.782 ng/mL. |
Application | |
Recommended Dose | FCM:1:50-1:200. |
Antibody Type | Monoclonal |
Subcellular Localization | Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Isoform A1: Expression is restricted to the lung. Isoform A2: Expression is restricted to the stomach mucosa where it is predominantly observed in the epithelial cells of the pit region and the base of the gastric glands including exocrine and endocrine c |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
Research Background | Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein: Human CLDN18 Protein |
Antigen Species | Human |
Gene Name | CLDN18 |
Gene ID | |
Uniprot ID | |
Biology Area | Signal transduction |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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