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Anti-Claudin-18 Antibody (5M288)

😃Good
Catalog No. TMAH-00274
Alias SFTPJ, SFTA5, CLDN18, CLDN 18, claudin 18

Anti-Claudin-18 Antibody (5M288) is an antibody targeting Claudin-18. Anti-Claudin-18 Antibody (5M288) can be used in ELISA,FCM.

Anti-Claudin-18 Antibody (5M288)

Anti-Claudin-18 Antibody (5M288)

😃Good
Catalog No. TMAH-00274Alias SFTPJ, SFTA5, CLDN18, CLDN 18, claudin 18
Anti-Claudin-18 Antibody (5M288) is an antibody targeting Claudin-18. Anti-Claudin-18 Antibody (5M288) can be used in ELISA,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2087-10 days
100 μL$3477-10 days
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Product Introduction

Bioactivity
Description
Anti-Claudin-18 Antibody (5M288) is an antibody targeting Claudin-18. Anti-Claudin-18 Antibody (5M288) can be used in ELISA,FCM.
SynonymsSFTPJ, SFTA5, CLDN18, CLDN 18, claudin 18
Ig Type
Human IgG1
Clone
5M288
Reactivity
Human
Verified Activity
1. Untransfected KATO3 cells surface (green line), transfected Human CLDN18.2 KATO3 stable cells surface (red line) and transfected Human CLDN18.1 NIH-3T3 stable cells surface (blue line) were stained with anti-CLDN18.2 antibody (2µg/1*10^6 cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
2. The Binding Activity of Human CLDN18.2 with Anti-CLDN18 recombinant antibody.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CLDN18.2 at 5 μg/mL can bind Anti-CLDN18 recombinant antibody, the EC50 is 2.947-8.782 ng/mL.
Application
Recommended Dose
FCM:1:50-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationCell junction, tight junction. Cell membrane; Multi-pass membrane protein.
Tissue SpecificityIsoform A1: Expression is restricted to the lung. Isoform A2: Expression is restricted to the stomach mucosa where it is predominantly observed in the epithelial cells of the pit region and the base of the gastric glands including exocrine and endocrine c
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPreservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
Research BackgroundPlays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human CLDN18 Protein
Antigen Species
Human
Gene Name
CLDN18
Gene ID
Uniprot ID
Biology Area
Signal transduction
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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