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Anti-QKI Antibody (4N982)
😃Good
Catalog No. TMAB-11968
Anti-QKI Antibody (4N982) is a Rabbit antibody targeting QKI. Anti-QKI Antibody (4N982) can be used in FCM, ICC/IF, IP, WB.
Anti-QKI Antibody (4N982)
Anti-QKI Antibody (4N982)
😃Good
Catalog No. TMAB-11968
Anti-QKI Antibody (4N982) is a Rabbit antibody targeting QKI. Anti-QKI Antibody (4N982) can be used in FCM, ICC/IF, IP, WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $150 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-QKI Antibody (4N982) is a Rabbit antibody targeting QKI. Anti-QKI Antibody (4N982) can be used in FCM, ICC/IF, IP, WB. |
| Ig Type | IgG |
| Clone | 4N982 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | FCM=1:50-100; ICC/IF=1:50-200; IP=1:20-50; WB=1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Cytoplasm. |
| Tissue Specificity | Expressed in the frontal cortex of brain. Down-regulated in the brain of schizophrenic patients. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | RNA reader protein, which recognizes and binds specific RNAs, thereby regulating RNA metabolic processes, such as pre-mRNA splicing, circular RNA (circRNA) formation, mRNA export, mRNA stability and/or translation.Involved in various cellular processes, such as mRNA storage into stress granules, apoptosis, lipid deposition, interferon response, glial cell fate and development. |
| Immunogen | A synthesized peptide: human QKI |
| Antigen Species | Human |
| Gene Name | QKI |
| Gene ID | |
| Protein Name | Protein quaking |
| Uniprot ID | |
| Function | RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B. Regulator of oligodendrocyte differentiation and maturation in the brain that may play a role in myelin and oligodendrocyte dysfunction in schizophrenia. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor. |
| Molecular Weight | Theoretical: 38 kDa. Actual: 38 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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