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  • Inhibitors & Agonists
    10532
    TargetMol | Inhibitors_Agonists
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    TargetMol | Inhibitors_Agonists
MRTX1133
T93032621928-55-8In house
MRTX1133 is a KRAS G12D inhibitor (KD=0.2 pM) that is potent, selective, and non-covalent. MRTX1133 exhibits inhibitory activity against KRAS G12D-mutated tumors, but not against KRAS wild-type tumors.
  • $197
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TargetMol | Inhibitor Hot
Y-27632 dihydrochloride
Y-27632 2HCl
T1725129830-38-2
Y-27632 dihydrochloride (Y-27632 2HCl) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II. Y-27632 dihydrochloride also inhibits isolation-induced apoptosis in mouse prostate stem or progenitor cells.
  • $33
In Stock
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TargetMol | Inhibitor Hot
G-418 disulfate
Geneticin sulfate, Geneticin, G418 Sulfate, Antibiotic G-418 sulfate
T6512108321-42-2
G-418 disulfate (Geneticin sulfate) is an aminoglycoside antibiotic that selectively inhibits eukaryotic protein synthesis by blocking peptide chain elongation.
  • $42
In Stock
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TargetMol | Inhibitor Hot
Adagrasib
MRTX849
T83692326521-71-3
Adagrasib (MRTX849) is an orally active and selective covalent inhibitor of KRAS G12C. Adagrasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Adagrasib exhibits inhibitory activity against KRAS G12C mutant tumors.
  • $59
In Stock
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TargetMol | Inhibitor Hot
Talmapimod
SCIO-469
T12871309913-83-5In house
Talmapimod (SCIO-469) is a selective, orally active, ATP-competitive p38α inhibitor with IC50 values of 9 nM for p38α and 90 nM for p38β. Talmapimod exhibits at least 2000-fold selectivity over a panel of 20 kinases, including other MAPKs.
  • $48
In Stock
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bc 11-38
T21865686770-80-9In house
BC 11-38 is a potent, selective PDE biodepressant which is mainly effective against PDE11 (IC50 : 0.28 μM).
  • $30
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Diclofenac
Voltaren, Diclofenacum
T019615307-86-5
Diclofenac (Diclofenacum) is a nonsteroidal benzeneacetic acid derivative with anti-inflammatory activity. Diclofenac binds and chelates both isoforms of cyclooxygenase (COX-1 and-2), thereby blocking the conversion of arachidonic acid to pro-inflammatory-proprostaglandins.
  • $42
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Diclofenac diethylamine
T043278213-16-8
Diclofenac Diethylamine, a non-selective COX inhibitor, is utilized as a nonsteroidal anti-inflammatory drug (NSAID).
  • $29
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Oxybenzone
KAHSCREEN BZ-3, Eusolex 4360, Escalol 567, Benzophenone 3
T0499131-57-7
Oxybenzone is a UV filter commonly used in tanning and skin protection agents. It is a derivative of benzophenone and is used as an endocrine disrupting chemical that penetrates the placental and blood-brain barriers. It impairs autophagy, alters epigenetic status and disrupts vitamin X-like receptor signaling in apoptotic neuronal cells.
  • $40
In Stock
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Benzyl butyl phthalate
butyl phenylmethyl ester, Butyl benzyl phthalate, BBP, 1,2-benzenedicarboxylic acid
T064085-68-7
Benzyl butyl phthalate (1,2-benzenedicarboxylic acid) is used as a plasticizer for PVC.
  • $30
In Stock
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Avobenzone
Butyl methoxydibenzoylmethane, BF2AVB
T069570356-09-1
Avobenzone is a dibenzoylmethane endocrine disruptor that binds directly to estrogen receptor β, acting as an estrogen agonist. It is one of the most widely used filters in sunscreens for photoprotection of skin in the UV band.
  • $48
In Stock
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Floxuridine
NSC 27640, FUDR, Deoxyfluorouridine, 5-Fluorouracil 2'-deoxyriboside
T096450-91-9
Floxuridine (FUDR) is an antimetabolite, floxuridine inhibits thymidylate synthase, resulting in disruption of DNA synthesis and cytotoxicity.
  • $30
In Stock
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Vildagliptin
NVP-LAF 237, LAF237
T1502274901-16-5
Vildagliptin (LAF237) is a cyanopyrrolidine-based, orally bioavailable inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Vildagliptin's cyano moiety undergoes hydrolysis and this inactive metabolite is excreted mainly via the urine.
  • $39
In Stock
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Diclofenac sodium
GP 45840
T155515307-79-6
Diclofenac sodium (GP 45840) is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
  • $45
In Stock
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plerixafor
JM3100, AMD-3329, AMD 3100
T1776110078-46-1
Plerixafor (AMD-3329), a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4.
  • $30
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Chlorphenesin
Gecophen, Chlorophenesin, Adermykon
T4507104-29-0
Chlorphenesin (Chlorophenesin) is an antigen-associated immunosuppressant that inhibits IgE-mediated histamine release. It is also used as an antimycotic agent.
  • $33
In Stock
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Iprodione
T511636734-19-7
Iprodione is a fungicide. Iprodione is also used in cannabis testing kits as a component of pesticide mixes.
  • $34
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Methyl cinnamate
T5552103-26-4
Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects.
  • $44
In Stock
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3-Bromopyruvic acid
Hexokinase II Inhibitor II, 3-BP, Bromopyruvic acid
T58821113-59-3
3-Bromopyruvic acid (Hexokinase II Inhibitor II, 3-BP) is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis hexokinase inhibition. It is inhibitor of tumour cell energy metabolism and chemopotentiator of platinum drugs.
  • $41
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Diclofenac Potassium
Voltfast, CGP-45840B, Cataflam
T647015307-81-0
Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.
  • $33
In Stock
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RA-9
T8464919091-63-7
RA-9 is a potent and selective proteasome-associated inhibitor of deubiquitinating enzymes (DUBs) with a favorable toxicity profile and anticancer activity, particularly effective in inducing apoptosis in ovarian cancer cell lines.
  • $45
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TargetMol | Inhibitor Sale
PTGR2-IN-1
PTGR2-IN-22
T8763349093-44-3
PTGR2-IN-1 is a potent inhibitor of PTGR2 (IC50: 0.7 μM) that enhances 15-keto-PGE2-dependent PPARγ transcriptional activity in PTGR2-transfected HEK293T cells.
  • $30
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TargetMol | Inhibitor Sale
CAN508
T8796140651-18-9
CAN508 is a potent ATP-competitive CDK9/cyclin T1 inhibitor with an IC50 of 0.35 μM. It also competitively inhibits Cdk2-cyclin E with respect to ATP, with Ki and IC50 values of 13.3 μM and 20 μM, respectively. CAN508 exhibits a 38-fold selectivity for CDK9/cyclin T over other CDK/cyclin complexes. [Antitumor activity.]
  • $30
In Stock
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TargetMol | Inhibitor Sale
Iriflophenone
TN176852591-10-3
Iriflophenone stimulates cells proliferation in  MCF-7 and T-47D human breast cancer.
  • $74
In Stock
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TargetMol | Inhibitor Sale