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Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK Membrane transporter/Ion channel
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Stem Cells Tyrosine Kinase/Adaptors Ubiquitination
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Search Results for "cells"

Libraries

Stem Cell Differentiation Compound Library Glycolysis Compound Library Cancer Cell Differentiation Compound Library Exosome Compound Library Targeted Therapy Drug Library Bioactive Compounds Library Max Cytoskeletal Signaling Pathway Compound Library Anti-Cancer Compound Library Reprogramming Compound Library Bioactive Compound Library TGF-beta/Smad Compound Library Anti-Viral Compound Library Inhibitor Library Calcium Antagonist Library Ion Channel Inhibitor Library Oxidation-Reduction Compound Library Anti-Metabolism Disease Compound Library Immuno-Oncology Compound Library Human Endogenous Metabolite Library Osteogenesis Compound Library Anti-Inflammatory Traditional Chinese Medicine Compound Library Glutamine Metabolism Compound Library Glycometabolism Compound Library Gut Microbial Metabolite Library DNA Damage & Repair Compound Library Antioxidant Compound Library Nuclear Receptor Compound Library Chemotherapy Drug Library Anti-Lung Cancer Compound Library DNA Damage and Repair Compound Library Plus Endocrinology-Hormone Compound Library Autophagy Compound Library Anti-Cancer Drug Library Anti-Cardiovascular Disease Compound Library Anti-Cancer Active Compound Library Anti-Colorectal Cancer Traditional Chinese Medicine Compound Library Anti-Cancer Clinical Compound Library Bioactive Lipid Compound Library HIF-1 Signaling Pathway Compound Library Anti-Cancer Approved Drug Library Serotonin Receptor-Targeted Compound Library Cell Cycle Compound Library Anti-Cancer Compound Library Plus Nucleotide Compound Library Saccharide and Glycoside Natural Product Library Anti-Breast Cancer Compound Library Sodium Channel Blocker Library Anti-Cancer Metabolism Compound Library Neuronal Signaling Compound Library Histamine & Melatonin Receptor-Targeted Compound Library Neural Regeneration Compound Library Protease Inhibitor Library Pyroptosis Compound Library Metabolism Compound Library Endoplasmic Reticulum Stress Compound Library Neurotransmitter Receptor Compound Library Lipid Metabolism Compound Library Anti-Alzheimer's Disease Compound Library Macrocyclic Compound Library
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Compounds

Cat No. Product Name
T9532 MRT-81 Others
MRT-81 是一种人和啮齿动物 smoothened 受体的有效拮抗剂，能够抑制 hedgehog 的活性，在 Shh-light2 细胞中的IC50值为 41 nM。它可用于研究癌症。
T8987 Epiblastin A Casein Kinase
Epiblastin A 是 ATP 竞争性的酪蛋白激酶 1 (CK1) 抑制剂，能够抑制 CK1α (IC50:8.9 µM)、 CK1δ (IC50:0.5 µM)、CK1 ɛ (IC50:4.7 µM)。它能够抑制 CK1 诱导外胚...
T9521 CHR-6494 TFA Others
CHR 6494 TFA 是一种选择性 haspin 抑制剂，IC50值为 2 nM，可抑制组蛋白 H3T3 的磷酸化。它诱导黑色素瘤、乳腺癌等肿瘤细胞凋亡，可研究癌症。
T8188 Podophyllotoxone Others , Microtubule Associated
Podophyllotoxone 是从八角莲根中分离得到的一种天然产物，能抑制微管蛋白聚合，具有抗癌活性。
TN1768 Iriflophenone Estrogen/progestogen Receptor , Estrogen Receptor/ERR
Iriflophenone 是从 Aquilaria sinensis 中分离得到，能诱导 MCF-7 和 T-47D 人乳腺癌细胞增殖。
T2040 OAC1 BAS 00287861 OCT
OAC1 是一种能够激活 Octamer 结合转录因子 4 的化合物。 它提高了 iPSC 重编程效率并加速重编程过程。
T7506 Yoda 1 Piezo Channel
Yoda 1 是Piezo1激动剂，能够激活纯化的 Piezo1 通道。
T2496 (Z)-Semaxinib SU5416 VEGFR
(Z)-Semaxinib 是一种有效的选择性 VEGFR(Flk-1/KDR) 抑制剂 (IC50: 1.23 μM)，对 VEGFR 的选择性是 PDGFRβ 的 20 倍，对 FGFR、InsR 和 EGFR 没有抑制作用。 Sema...
T5821 BC-1215 Others
BC-1215 是一种 F-box protein 3 抑制剂。它能够稳定 TRAF1-TRAF6 来抑制 Fbxo3-TRAF 激活途径。它与 ApaG 相互作用，阻碍来自人 PBMC 广谱 TH1 细胞因子的分泌。
T2S1040 Jolkinolide B PI3K , Caspase , p38 MAPK , NF-κB , IL Receptor , Akt , mTOR , BCL , JAK , JNK , STAT , ERK , TNF
Jolkinolide B 是一种从 Euphorbia fischeriana Steud 的根中分离出来的具有生物活性的二萜。 Jolkinolide B 诱导癌细胞凋亡。 Jolkinolide B 可用于预防和治疗骨溶解的研究。
T3887 Rosarin Others
Rosarin 是从玫瑰红景天中分离出来的肉桂醇糖苷。它抑制小鼠肾脏和大脑前额皮层中促炎因子 iNOS，IL-1β 和 TNF-α 的表达。它具有抗炎和神经保护作用。
TN1546 Dactylorhin A NO Synthase
Dactylorhin A 是一种琥珀酸衍生物酯，分离自 Gymnadenia conopsea 根茎中。它对 RAW 264.7 巨噬细胞产生 NO 有中等程度的抑制作用。
T13741 Isoviolanthin 异佛莱心苷,异佛来心苷 Others
Isoviolanthin 是一种黄酮类苷类化合物，提取自铁皮石斛叶中。它能减少 TGF-β1 处理的 HCC 细胞的迁移和入侵能力，对正常细胞没有毒性影响，对转移性肝癌晚期具有潜在的研究价值。
T6793 BRD7552 Others
BRD7552 是PDX1转录因子诱导剂，它能够上调人类原代胰岛和导管细胞中 PDX1 的表达，诱导 PDX1 启动子的表观遗传变化与转录激活一致，提高胰岛素表达。其中 PDX1 是参与胰腺发育和β细胞功能的关键转录因子。
T12928 SK33 Androgen Receptor
SK33 是一种有效的组织选择性抗雄激素药物，是一种肌醇类似物，能够降低雄激素受体 (AR) 的转录活性。
T7814 Alloxan monohydrate Proteasome
Alloxan Monohydrate 是一种能够引起糖尿病的致糖尿病药物。它作为蛋白酶体抑制剂，破坏胰腺中能够分泌胰岛素的B 细胞，导致实验动物患糖尿病。
T0480 Doxofylline Doxophylline,多索茶碱 Adenosine Receptor , PDE
Doxofylline 是腺苷 A1 受体拮抗剂，且能抑制磷酸二酯酶 IV，用于治疗哮喘。
T5116 Iprodione Reactive Oxygen Species , Antifungal , Others
Iprodione 是一种二甲酰亚胺类的高度特异性杀菌剂，能通过产生自由氧自由基引起氧化损伤。
T15461 Halopemide Dopamine Receptor , Phospholipase , Others
Halopemide 是一种有效的 PLD 抑制剂（对人 PLD1 和 PLD2 的 IC50 = 220 和 310 nM）。 Halopemid 是多巴胺受体的拮抗剂。Halopemid 可用于精神药物研究。
T19777 ODQ Guanylate cyclase , Others , Apoptosis
ODQ 是一种选择性可溶性的鸟苷酰环化酶抑制剂，可增强顺铂促人间皮瘤细胞凋亡的作用。
MRT-81
T9532
synonym:
Target:
Epiblastin A
T8987
synonym:
Target:
CHR-6494 TFA
T9521
synonym:
Target:
Podophyllotoxone
T8188
synonym:
Target:
Iriflophenone
TN1768
synonym:
Target:
OAC1
T2040
synonym: BAS 00287861
Target:
Yoda 1
T7506
synonym:
Target:
(Z)-Semaxinib
T2496
synonym: SU5416
Target:
BC-1215
T5821
synonym:
Target:
Jolkinolide B
T2S1040
synonym:
Target:
Rosarin
T3887
synonym:
Target:
Dactylorhin A
TN1546
synonym:
Target:
Isoviolanthin
T13741
synonym: 异佛莱心苷,异佛来心苷
Target:
BRD7552
T6793
synonym:
Target:
SK33
T12928
synonym:
Target:
Alloxan monohydrate
T7814
synonym:
Target:
Doxofylline
T0480
synonym: Doxophylline,多索茶碱
Target:
Iprodione
T5116
synonym:
Target:
Halopemide
T15461
synonym:
Target:
ODQ
T19777
synonym:
Target:
1 2 3 4 5 ... 270
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