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(E/Z)-MitoTam (iodide, hydriodide) is a mixture of E/Z isomers of MitoTam iodide, hydriodide. This compound, a derivative of tamoxifen, acts as an electron transport chain (ETC) inhibitor, preventing changes in mitochondrial membrane potential and affecting mitochondrial morphology in aging cells. It is an effective anticancer agent, impeding the formation of respiratory complex I (CI- respiration) and supercomplexes (SCs) in breast cancer cells, and can induce apoptosis (apoptosis).
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
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| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | (E/Z)-MitoTam (iodide, hydriodide) is a mixture of E/Z isomers of MitoTam iodide, hydriodide. This compound, a derivative of tamoxifen, acts as an electron transport chain (ETC) inhibitor, preventing changes in mitochondrial membrane potential and affecting mitochondrial morphology in aging cells. It is an effective anticancer agent, impeding the formation of respiratory complex I (CI- respiration) and supercomplexes (SCs) in breast cancer cells, and can induce apoptosis (apoptosis). |
| Synonyms | MitoTax iodide, hydriodide |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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