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LPS-PG

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Catalog No. T210365

LPS-PG is a lipopolysaccharide from Porphyromonas gingivalis (P. gingivalis). It functions as a crucial virulence factor in the pathogenesis of periodontal disease by activating immune cells through Toll-like receptor 2 (TLR2), rather than the Escherichia coli (E. coli) receptor, Toll-like receptor 4 (TLR4). A lipoprotein from LPS-PG has been identified as the primary component responsible for TLR2-mediated cell activation.

LPS-PG

LPS-PG

😃Good
Catalog No. T210365
LPS-PG is a lipopolysaccharide from Porphyromonas gingivalis (P. gingivalis). It functions as a crucial virulence factor in the pathogenesis of periodontal disease by activating immune cells through Toll-like receptor 2 (TLR2), rather than the Escherichia coli (E. coli) receptor, Toll-like receptor 4 (TLR4). A lipoprotein from LPS-PG has been identified as the primary component responsible for TLR2-mediated cell activation.
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Product Introduction

Bioactivity
Description
LPS-PG is a lipopolysaccharide from Porphyromonas gingivalis (P. gingivalis). It functions as a crucial virulence factor in the pathogenesis of periodontal disease by activating immune cells through Toll-like receptor 2 (TLR2), rather than the Escherichia coli (E. coli) receptor, Toll-like receptor 4 (TLR4). A lipoprotein from LPS-PG has been identified as the primary component responsible for TLR2-mediated cell activation.
In vitro
LPS-PG (1 μg/mL, 12 h) effectively induces acute inflammation in HGF-1 cells.
Chemical Properties
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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