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Anti-CD11b ITAM Antibody (5C987) is a Mouse antibody targeting CD11b ITAM. Anti-CD11b ITAM Antibody (5C987) can be used in IP,IF,FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $297 | 7-10 days | |
100 μL | $498 | 7-10 days |
Description | Anti-CD11b ITAM Antibody (5C987) is a Mouse antibody targeting CD11b ITAM. Anti-CD11b ITAM Antibody (5C987) can be used in IP,IF,FCM. |
Synonyms | SLEB6, Neutrophil adherence receptor alpha M subunit, Neutrophil adherence receptor, MO1A, Mo1, alpha subunit, MGC117044, Macrophage antigen alpha polypeptide, Mac-1a, MAC1A, Mac1, alpha subunit, MAC1, MAC 1, Ly-40, Leukocyte adhesion receptor MO1, ITGAM, ITAM_HUMAN, integrin, alpha M (complement component 3 receptor 3 subunit), Integrin subunit alpha M, Integrin beta 2 alpha subunit, Integrin alpha-M, Integrin alpha M chain, Integrin Alpha M, F730045J24Rik, CR3A, CR-3 alpha chain, CR3, CR 3 alpha chain (CR3A), CR 3 alpha chain, Complement receptor type 3, alpha subunit, Complement Component Receptor 3 Alpha, Complement component 3 receptor 3 subunit, Cell surface glycoprotein MAC-1 subunit alpha, CD49d, CD11b/CD18, CD11b, CD11 antigen-like family member B, CD11 antigen like family member B, Antigen CD11b p170, antigen CD11b (p170) |
Reactivity | Human,Mouse |
Verified Activity | 1. Western blot analysis of Integrin αM expression in human PBL whole cell lysate immunoprecipitated with Integrin αM (2LPM19c) and detected with Integrin αM (H-61). 2. Immunofluorescence staining of methanol-fixed RAW 264.7 cells showing membrane staining. 3. FCM analysis of human peripheral blood leukocytes. Black line histogram represents the isotype control, normal mouse IgG1. 4. FCM analysis of human peripheral blood leukocytes. Black line histogram represents the isotype control, normal mouse IgG1. |
Application | |
Recommended Dose | IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate); FCM: 1 μg per 1 x 106 cells |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | Hybridoma Monoclonal Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | Integrin ?M, also designated complement component receptor-3 ?, CD11b (p170), macrophage antigen a polypeptide, cell surface glycoprotein Mac-1 a subunit, MAC1A, MO1A and ITGAM) is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin ?M combines with the Integrin ∫2 to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin ?M/∫2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. |
Conjucates | Unconjugated |
Immunogen | Peptide |
Uniprot ID |
Molecular Weight | Theoretical: 170 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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