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Xinidamine

Name: Xinidamine
Brand: TargetMol
SKU: T35182
Price: 147 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: Xinidaminum, Xinidamino, BRN 0891979) Copy Product Info

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Synonyms: Xinidaminum, Xinidamino, BRN 0891979

Catalog No. T35182 Copy Product Info

Purity: 98.12%

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Xinidamine (BRN 0891979) has antitumor activity and can be used to study benign prostatic hyperplasia, macular degeneration and prostatic intraepithelial neoplasia .Xinidamine inhibits the proliferation of PWR-1E cells with an IC50 of 4 μM.

Cas No. 50264-78-3

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Pack Size	Price	USA Stock	Global Stock
1 mg	$147	In Stock	In Stock
5 mg	$348	In Stock	In Stock
10 mg	$475	In Stock	In Stock
25 mg	$667	In Stock	In Stock
50 mg	$826	In Stock	In Stock
100 mg	$1,050	In Stock	In Stock
200 mg	$1,370	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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Custom-made molecule. TargetMol’s expert synthesis team delivers cost-effective solutions. Contact us for inquiries. Committed to serving you.

For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:98.12%

Appearance:Solid

Color:White

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COA HPLC HNMR

Product Introduction

Xinidamine AI Summary

Xinidamine has demonstrated significant antispermatogenic activity in Long-Evans rats following a single administration. The reduction in testes weight served as the primary measure of bioactivity, with a median effective dose (MED) identified at 101.0 mg/kg after a period of 5 days..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Xinidamine (BRN 0891979) has antitumor activity and can be used to study benign prostatic hyperplasia, macular degeneration and prostatic intraepithelial neoplasia .Xinidamine inhibits the proliferation of PWR-1E cells with an IC50 of 4 μM.
Targets & IC50	Proliferation (PWR-1E cells):4 μM
Synonyms	Xinidaminum, Xinidamino, BRN 0891979

Chemical Properties

Molecular Weight	280.32
Formula	C₁₇H₁₆N₂O₂
Cas No.	50264-78-3
Smiles	C(N1C=2C(C(C(O)=O)=N1)=CC=CC2)C3=C(C)C=C(C)C=C3
Relative Density.	1.22g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (178.37 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5674 mL	17.8368 mL	35.6735 mL	178.3676 mL
5 mM	0.7135 mL	3.5674 mL	7.1347 mL	35.6735 mL
10 mM	0.3567 mL	1.7837 mL	3.5674 mL	17.8368 mL
20 mM	0.1784 mL	0.8918 mL	1.7837 mL	8.9184 mL
50 mM	0.0713 mL	0.3567 mL	0.7135 mL	3.5674 mL
100 mM	0.0357 mL	0.1784 mL	0.3567 mL	1.7837 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc