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Vonlerizumab

(Synonyms: Anti-TNFRSF4/OX40/CD134 Antibody) Copy Product Info
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Synonyms: Anti-TNFRSF4/OX40/CD134 Antibody

Catalog No. T77368 Copy Product Info
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Vonlerizumab (Anti-TNFRSF4/OX40/CD134 Antibody) is a humanized monoclonal antibody that specifically targets TNFRSF4/OX40/CD134. As an OX40 agonist, vonlerizumab promotes the proliferation of effector T cells and suppresses the function of regulatory T cells by binding to and activating the OX40 receptor on the surface of T cells, thereby enhancing the antitumor immune response. Vonlerizumab can be used in cancer immunotherapy research.
Vonlerizumab
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$358-In Stock
5 mg$1,120-In Stock
10 mg$1,790-In Stock
25 mg$3,360-In Stock
50 mgPreferential-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:98.93% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Vonlerizumab (Anti-TNFRSF4/OX40/CD134 Antibody) is a humanized monoclonal antibody that specifically targets TNFRSF4/OX40/CD134. As an OX40 agonist, vonlerizumab promotes the proliferation of effector T cells and suppresses the function of regulatory T cells by binding to and activating the OX40 receptor on the surface of T cells, thereby enhancing the antitumor immune response. Vonlerizumab can be used in cancer immunotherapy research.
SynonymsAnti-TNFRSF4/OX40/CD134 Antibody
Reactivity
Human
Verified Activity
OX40-NF-κB-Jurkat cells at 1×10^5 cell/well can bind Vonlerizumab. The EC50 is 0.008 μg/mL.
Vonlerizumab
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetTNFRSF4/OX40/CD134
Chemical Properties
Molecular Weight145.22 kDa
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
StorageStore at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Vonlerizumab chemical structure | Vonlerizumab molecular weight