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Anticancer agent 46

Name: Anticancer agent 46
Brand: TargetMol
SKU: T60852
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T60852Cas No. 2426686-17-9

Anticancer agent 46 is a potent anti-cancer agent, showing anti-proliferative activity in cellular assays, with an IC50 of 0.986 μM against MGC803 cells.

Anticancer agent 46

🥰Excellent

Purity: 97.08%

Catalog No. T60852Cas No. 2426686-17-9

Anticancer agent 46 is a potent anti-cancer agent, showing anti-proliferative activity in cellular assays, with an IC50 of 0.986 μM against MGC803 cells.

Pack Size	Price	Availability
25 mg	$29	In Stock
50 mg	$35	In Stock
100 mg	$55	In Stock

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Batch Information

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Purity:97.08%

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COA HNMR HPLC

Product Introduction

Bioactivity

Description	Anticancer agent 46 is a potent anti-cancer agent, showing anti-proliferative activity in cellular assays, with an IC50 of 0.986 μM against MGC803 cells.
Targets&IC50	MGC-803 cells:0.986 µM

Chemical Properties

Molecular Weight	319.81
Formula	C₁₅H₁₄ClN₃OS
Cas No.	2426686-17-9
Smiles	C(=N\NC(NC1=CC=CC=C1)=S)(\C)/C2=C(O)C=CC(Cl)=C2
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (187.61 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1269 mL	15.6343 mL	31.2686 mL	156.3428 mL
5 mM	0.6254 mL	3.1269 mL	6.2537 mL	31.2686 mL
10 mM	0.3127 mL	1.5634 mL	3.1269 mL	15.6343 mL
20 mM	0.1563 mL	0.7817 mL	1.5634 mL	7.8171 mL
50 mM	0.0625 mL	0.3127 mL	0.6254 mL	3.1269 mL
100 mM	0.0313 mL	0.1563 mL	0.3127 mL	1.5634 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc