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IMC-D11

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Catalog No. T9901A-809
Alias LY-3076226 antibody

IMC-D11 is a fully human monoclonal antibody that specifically targets the extracellular domain of fibroblast growth factor receptor 3 (FGFR3) and blocks ligand-induced activation. By inhibiting FGFR3 phosphorylation and its downstream signaling cascades, this antibody effectively suppresses the growth and survival of various FGFR3-dependent tumor cells.

IMC-D11

IMC-D11

Copy Product Info
😃Good
Catalog No. T9901A-809Alias LY-3076226 antibody
IMC-D11 is a fully human monoclonal antibody that specifically targets the extracellular domain of fibroblast growth factor receptor 3 (FGFR3) and blocks ligand-induced activation. By inhibiting FGFR3 phosphorylation and its downstream signaling cascades, this antibody effectively suppresses the growth and survival of various FGFR3-dependent tumor cells.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
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5 mgInquiryInquiryInquiry
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
IMC-D11 is a fully human monoclonal antibody that specifically targets the extracellular domain of fibroblast growth factor receptor 3 (FGFR3) and blocks ligand-induced activation. By inhibiting FGFR3 phosphorylation and its downstream signaling cascades, this antibody effectively suppresses the growth and survival of various FGFR3-dependent tumor cells.
SynonymsLY-3076226 antibody
Reactivity
Human
Application
FACS
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Uniprot ID
TargetFGFR3/CD333
Chemical Properties
Antibody Information
IsotypeIgG1-Lambda
Storage & Solubility Information
Storagestore at low temperature | store at -20°C | Shipping with blue ice.

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