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IMC-D11
(Synonyms: LY-3076226 antibody) Copy Product Info
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Synonyms: LY-3076226 antibody
Catalog No. T9901A-809 Copy Product Info
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IMC-D11 is a fully human monoclonal antibody that specifically targets the extracellular domain of fibroblast growth factor receptor 3 (FGFR3) and blocks ligand-induced activation. By inhibiting FGFR3 phosphorylation and its downstream signaling cascades, this antibody effectively suppresses the growth and survival of various FGFR3-dependent tumor cells.
IMC-D11
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | Inquiry | Inquiry | Inquiry | |
| 5 mg | Inquiry | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | IMC-D11 is a fully human monoclonal antibody that specifically targets the extracellular domain of fibroblast growth factor receptor 3 (FGFR3) and blocks ligand-induced activation. By inhibiting FGFR3 phosphorylation and its downstream signaling cascades, this antibody effectively suppresses the growth and survival of various FGFR3-dependent tumor cells. |
| Synonyms | LY-3076226 antibody |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | FGFR3/CD333 |
| Isotype | IgG1-Lambda |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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