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HeFi-1
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Catalog No. T9901A-1744 Copy Product Info
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HeFi-1 is a mouse anti-CD30 IgG1 monoclonal antibody that targets the ligand-binding site on CD30. It can inhibit the growth of tumor cells with high CD30 expression and induce eosinophil apoptosis (apoptosis). HeFi-1 is applicable in research on cancer or inflammatory diseases, such as anaplastic large cell lymphoma (ALCL) and asthma.
HeFi-1
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | Inquiry | Inquiry | Inquiry | |
| 5 mg | Inquiry | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | HeFi-1 is a mouse anti-CD30 IgG1 monoclonal antibody that targets the ligand-binding site on CD30. It can inhibit the growth of tumor cells with high CD30 expression and induce eosinophil apoptosis (apoptosis). HeFi-1 is applicable in research on cancer or inflammatory diseases, such as anaplastic large cell lymphoma (ALCL) and asthma. |
| In vitro | HeFi-1 (0.1 ng/μL, 1 hour) can specifically bind to Karpas299 cells, achieving a binding rate of over 90%. At a concentration of 20 μg/mL for 48 hours, HeFi-1 significantly inhibits the proliferation of Karpas299 cells and induces G1 phase arrest. Additionally, HeFi-1 (20 μg/mL, 12-24 hours) significantly induces eosinophil apoptosis. |
| In vivo | Administered intravenously at a dose of HeFi-1 (100 μg) once a week for four weeks, the compound significantly prolongs the survival of SCID/NOD wild-type and FcRγ -/- Karpas299 lymphoma-bearing mice. |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: HeFi-1 in vivo | HeFi-1 in vitro
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