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Demethoxyfumitremorgin C

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Catalog No. TN6059Cas No. 111768-16-2

Demethoxyfumitremorgin C and tryprostatin B are fungal inhibitors of mammalian cell cycle progression at the G(2)/M transition. Demethoxyfumitremorgin C inhibits the proliferation of PC3 human prostate cancer cells via the intrinsic (mitochondrial) and extrinsic pathway, followed by downstream events leading to apoptotic cell death, it could therefore, serve as a useful agent to treat human advanced prostate cancer.

Demethoxyfumitremorgin C

Demethoxyfumitremorgin C

😃Good
Catalog No. TN6059Cas No. 111768-16-2
Demethoxyfumitremorgin C and tryprostatin B are fungal inhibitors of mammalian cell cycle progression at the G(2)/M transition. Demethoxyfumitremorgin C inhibits the proliferation of PC3 human prostate cancer cells via the intrinsic (mitochondrial) and extrinsic pathway, followed by downstream events leading to apoptotic cell death, it could therefore, serve as a useful agent to treat human advanced prostate cancer.
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Product Introduction

Bioactivity
Description
Demethoxyfumitremorgin C and tryprostatin B are fungal inhibitors of mammalian cell cycle progression at the G(2)/M transition. Demethoxyfumitremorgin C inhibits the proliferation of PC3 human prostate cancer cells via the intrinsic (mitochondrial) and extrinsic pathway, followed by downstream events leading to apoptotic cell death, it could therefore, serve as a useful agent to treat human advanced prostate cancer.
Chemical Properties
Molecular Weight349.434
FormulaC21H23N3O2
Cas No.111768-16-2
Smiles[H][C@@]12CCCN1C(=O)[C@]1([H])Cc3c([nH]c4ccccc34)[C@H](C=C(C)C)N1C2=O |wU:1.0,8.9,wD:20.23,(-6.13,-6.74,;-5.74,-5.25,;-7.26,-5.51,;-7.97,-4.14,;-6.89,-3.04,;-5.51,-3.73,;-4.08,-3.17,;-3.85,-1.64,;-2.87,-4.13,;-2.64,-2.6,;-1.44,-3.56,;-.23,-4.52,;-.46,-6.04,;.91,-6.73,;1.99,-5.63,;3.53,-5.7,;4.36,-4.4,;3.65,-3.04,;2.11,-2.97,;1.28,-4.27,;-1.9,-6.61,;-2.12,-8.13,;-.92,-9.09,;-1.15,-10.61,;.51,-8.53,;-3.1,-5.65,;-4.53,-6.21,;-4.76,-7.74,)|
Relative Density.1.33 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Keywords

Demethoxyfumitremorgin C
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