Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Anticancer Agent 110 exhibits potent in vitro anti-leukemia activity, demonstrating high cytotoxicity against K-562 lineage chronic myelogenous leukemia cells at nanomolar concentrations. It induces DNA damage and subsequently triggers apoptosis [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | Anticancer Agent 110 exhibits potent in vitro anti-leukemia activity, demonstrating high cytotoxicity against K-562 lineage chronic myelogenous leukemia cells at nanomolar concentrations. It induces DNA damage and subsequently triggers apoptosis [1]. |
In vitro | Anticancer agent 110 (化合物 3d) demonstrates inhibitory effects on leukemia K-562 cells within a concentration range of 0.01 μM to 100 μM, with an IC50 of 0.7 μM [1]. At concentrations of 70 nM and 700 nM over 24 hours, this agent induces a higher level of DNA damage in K-562 cells [1] and also provokes morphological changes consistent with apoptosis in these leukemia cells [1]. |
Molecular Weight | 380.4 |
Formula | C18H13FN6OS |
CAS No. | 887349-03-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Anticancer agent 110 887349-03-3 Apoptosis inhibitor inhibit