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Methyl retinoate
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Catalog No. T77599Cas No. 339-16-2
Alias Retinoic acid, methyl ester
Methyl retinoate (Retinoic acid, methyl ester) induces aseptic inflammation at the site of administration in in vivo experiments, which causes an increase in the number of leukocytes in the blood and a decrease in the levels of red blood cells and Hb.Methyl retinoate promotes spontaneous leukemia.Methyl retinoate can be Used in the treatment of gastric hypertrophy and ulcers due to vitamin A deficiency.
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Methyl retinoate
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Purity: 97.85%
Catalog No. T77599Alias Retinoic acid, methyl esterCas No. 339-16-2
Methyl retinoate (Retinoic acid, methyl ester) induces aseptic inflammation at the site of administration in in vivo experiments, which causes an increase in the number of leukocytes in the blood and a decrease in the levels of red blood cells and Hb.Methyl retinoate promotes spontaneous leukemia.Methyl retinoate can be Used in the treatment of gastric hypertrophy and ulcers due to vitamin A deficiency.
Translated with www.DeepL.com/Translator (free version)
Translated with www.DeepL.com/Translator (free version)
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $82 | - | In Stock | |
| 5 mg | $181 | - | In Stock | |
| 10 mg | $267 | - | In Stock | |
| 25 mg | $413 | - | In Stock | |
| 50 mg | $571 | - | In Stock | |
| 100 mg | $763 | - | In Stock | |
| 200 mg | $1,030 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information
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Purity:97.85%
Appearance:Solid
Color:Yellow
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Product Introduction
Methyl retinoate AI Summary
Methyl retinoate induces morphological transformation of rat ASK cells into astrocytes after 1 hour, with an effective dose (ED50) greater than 25.0 µM, as observed under light microscopy. Additionally, it reverses keratinized lesions in vitamin A deficient hamster tracheal organ cultures, reducing keratin and keratohyaline granules at specific concentrations after 7 days. The compound also increases RNA content in mouse epidermal cells at varying concentrations after 3 days, suggesting a potential stimulatory effect on RNA synthesis or cellular activity..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Methyl retinoate (Retinoic acid, methyl ester) induces aseptic inflammation at the site of administration in in vivo experiments, which causes an increase in the number of leukocytes in the blood and a decrease in the levels of red blood cells and Hb.Methyl retinoate promotes spontaneous leukemia.Methyl retinoate can be Used in the treatment of gastric hypertrophy and ulcers due to vitamin A deficiency. Translated with www.DeepL.com/Translator (free version) |
| Synonyms | Retinoic acid, methyl ester |
| Molecular Weight | 314.46 |
| Formula | C21H30O2 |
| Cas No. | 339-16-2 |
| Smiles | C(=C/C(=C/C=C/C(=C/C(OC)=O)/C)/C)\C=1C(C)(C)CCCC1C |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 60 mg/mL (190.8 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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