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(Rac)-Roscovitine ((Rac)-Seliciclib) is a selective inhibitor of cyclin-dependent kinases (CDKs). It competes with ATP for binding at the active site of CDKs, thereby inhibiting their phosphorylation activity. This compound induces apoptosis in cancer cells and holds potential for the study of conditions like cancer, neurodegenerative diseases, heart diseases, viral and protozoal infections, glomerulonephritis, and chronic inflammation, all of which are associated with CDK dysregulation.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | Inquiry | 10-14 weeks | |
50 mg | Inquiry | 10-14 weeks |
Description | (Rac)-Roscovitine ((Rac)-Seliciclib) is a selective inhibitor of cyclin-dependent kinases (CDKs). It competes with ATP for binding at the active site of CDKs, thereby inhibiting their phosphorylation activity. This compound induces apoptosis in cancer cells and holds potential for the study of conditions like cancer, neurodegenerative diseases, heart diseases, viral and protozoal infections, glomerulonephritis, and chronic inflammation, all of which are associated with CDK dysregulation. |
Synonyms | (Rac)-Seliciclib, (Rac)-CYC202 |
Molecular Weight | 354.449 |
Formula | C19H26N6O |
Cas No. | 186692-44-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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