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Neurodazine

Name: Neurodazine
Brand: TargetMol
SKU: T16287
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T16287Cas No. 937807-66-4

Neurodazine is a neural inducer that promotes the differentiation of pluripotent cells into neuronal cells.Neurodazine promotes differentiation by activating Wnt and Shh signaling.

Neurodazine

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Purity: 98.01%

Catalog No. T16287Cas No. 937807-66-4

Neurodazine is a neural inducer that promotes the differentiation of pluripotent cells into neuronal cells.Neurodazine promotes differentiation by activating Wnt and Shh signaling.

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$52	In Stock	In Stock
5 mg	$82	In Stock	In Stock
10 mg	$118	In Stock	In Stock
25 mg	$193	In Stock	In Stock
50 mg	$286	In Stock	In Stock
100 mg	$423	-	In Stock
1 mL x 10 mM (in DMSO)	$30	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:98.01%

Appearance:Solid

Color:Yellow

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Neurodazine is a neural inducer that promotes the differentiation of pluripotent cells into neuronal cells.Neurodazine promotes differentiation by activating Wnt and Shh signaling.
In vitro	Treatment with Neurodazine (5 μM; 1-10 d) induces the expression of neuron-specific markers in P19 cells[2]. Neurodazine selectively suppresses astrocyte differentiation of P19 cells[2].

Chemical Properties

Molecular Weight	456.92
Formula	C₂₇H₂₁ClN₂O₃
Cas No.	937807-66-4
Smiles	COc1ccc(cc1)-c1nc([nH]c1-c1ccc(OC)cc1)-c1ccc(o1)-c1cccc(Cl)c1
Relative Density.	1.252 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (175.09 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1886 mL	10.9428 mL	21.8857 mL	109.4283 mL
5 mM	0.4377 mL	2.1886 mL	4.3771 mL	21.8857 mL
10 mM	0.2189 mL	1.0943 mL	2.1886 mL	10.9428 mL
20 mM	0.1094 mL	0.5471 mL	1.0943 mL	5.4714 mL
50 mM	0.0438 mL	0.2189 mL	0.4377 mL	2.1886 mL
100 mM	0.0219 mL	0.1094 mL	0.2189 mL	1.0943 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc