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Troriluzole
🥰Excellent
Catalog No. T17174Cas No. 1926203-09-9
Alias FC 4157, BHV-4157a, BHV-4157, BHV4157, BHV 4157
Troriluzole is an orally active glutamate modulator with anticancer activity.Troriluzole enhances the expression of excitatory amino acid transporters located in glial cells and is used in the study of spinocerebellar ataxia, Alzheimer's disease, and generalized anxiety disorder (GAD).
Troriluzole
🥰Excellent
Purity: 97.14%
Catalog No. T17174Alias FC 4157, BHV-4157a, BHV-4157, BHV4157, BHV 4157Cas No. 1926203-09-9
Troriluzole is an orally active glutamate modulator with anticancer activity.Troriluzole enhances the expression of excitatory amino acid transporters located in glial cells and is used in the study of spinocerebellar ataxia, Alzheimer's disease, and generalized anxiety disorder (GAD).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $100 | In Stock | |
| 5 mg | $247 | In Stock | |
| 10 mg | $396 | In Stock | |
| 25 mg | $728 | In Stock | |
| 50 mg | $1,160 | In Stock | |
| 100 mg | $1,730 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $272 | In Stock |
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Purity:97.14%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Troriluzole is an orally active glutamate modulator with anticancer activity.Troriluzole enhances the expression of excitatory amino acid transporters located in glial cells and is used in the study of spinocerebellar ataxia, Alzheimer's disease, and generalized anxiety disorder (GAD). |
| In vitro | Troriluzole is an EAAT2 modulator, NMDA receptor antagonist, and Nav1.5 blocker, commonly used in research on neurological disorders such as obsessive-compulsive disorder[1]. |
| Synonyms | FC 4157, BHV-4157a, BHV-4157, BHV4157, BHV 4157 |
| Molecular Weight | 419.38 |
| Formula | C15H16F3N5O4S |
| Cas No. | 1926203-09-9 |
| Smiles | CN(CC(=O)Nc1nc2ccc(OC(F)(F)F)cc2s1)C(=O)CNC(=O)CN |
| Relative Density. | 1.518 g/cm3 (Predicted) |
| Sequence | H-Gly-Gly-Sar-Unk |
| Sequence Short | GGG |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 30 mg/mL (71.53 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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