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VRT-325

Name: VRT-325
Brand: TargetMol
SKU: T35074
Price: 350 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T35074Cas No. 815592-21-3

Alias VRT-534, VRT325, VRT 325, CFcor-325, CFcor325, CFcor 325, CF-106951

VRT-325 can repair folding defects by promoting dimerization of the two NBDs or by promoting folding of the TMD.VRT-325 accelerates the healing rate of CF cell monolayers.

VRT-325

🥰Excellent

Purity: 99.15%

Catalog No. T35074Alias VRT-534, VRT325, VRT 325, CFcor-325, CFcor325, CFcor 325, CF-106951Cas No. 815592-21-3

VRT-325 can repair folding defects by promoting dimerization of the two NBDs or by promoting folding of the TMD.VRT-325 accelerates the healing rate of CF cell monolayers.

Pack Size	Price	Availability
1 mg	$350	In Stock
5 mg	$970	In Stock
10 mg	$1,200	In Stock
25 mg	$1,590	In Stock
50 mg	$1,980	In Stock
100 mg	$2,500	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.15%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	VRT-325 can repair folding defects by promoting dimerization of the two NBDs or by promoting folding of the TMD.VRT-325 accelerates the healing rate of CF cell monolayers.
Synonyms	VRT-534, VRT325, VRT 325, CFcor-325, CFcor325, CFcor 325, CF-106951

Chemical Properties

Molecular Weight	510.65
Formula	C₂₇H₃₄N₄O₄S
Cas No.	815592-21-3
Smiles	O(C=1C2=C(N=C(C(C)N3CCN(S(=O)(=O)C4=CC=C(OC)C=C4)CC3)N1)C=CC=C2)C5CCCCC5
Relative Density.	1.268 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (88.12 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9583 mL	9.7914 mL	19.5829 mL	97.9144 mL
5 mM	0.3917 mL	1.9583 mL	3.9166 mL	19.5829 mL
10 mM	0.1958 mL	0.9791 mL	1.9583 mL	9.7914 mL
20 mM	0.0979 mL	0.4896 mL	0.9791 mL	4.8957 mL
50 mM	0.0392 mL	0.1958 mL	0.3917 mL	1.9583 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc