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CW 008

🥰Excellent
Catalog No. T31124Cas No. 1134613-19-6

CW 008 is an agonist of the cAMP/PKA/CREB pathway, promoting osteogenic differentiation of bone marrow-derived mesenchymal stem cells (MSCs), inhibiting leptin secretion, and enhancing alkaline phosphatase (ALP) activity. It is also regarded as a PKA activator in experimental studies.

CW 008

CW 008

🥰Excellent
Purity: 97.39%
Catalog No. T31124Cas No. 1134613-19-6
CW 008 is an agonist of the cAMP/PKA/CREB pathway, promoting osteogenic differentiation of bone marrow-derived mesenchymal stem cells (MSCs), inhibiting leptin secretion, and enhancing alkaline phosphatase (ALP) activity. It is also regarded as a PKA activator in experimental studies.
Pack SizePriceAvailabilityQuantity
1 mg$73In Stock
5 mg$176In Stock
10 mg$289In Stock
25 mg$489In Stock
50 mg$698In Stock
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Purity:97.39%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
CW 008 is an agonist of the cAMP/PKA/CREB pathway, promoting osteogenic differentiation of bone marrow-derived mesenchymal stem cells (MSCs), inhibiting leptin secretion, and enhancing alkaline phosphatase (ALP) activity. It is also regarded as a PKA activator in experimental studies.
Chemical Properties
Molecular Weight420.37
FormulaC21H14F2N6O2
Cas No.1134613-19-6
Relative Density.no data available
ColorYellow
AppearanceSolid
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 12 mg/mL (28.55 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3789 mL11.8943 mL23.7886 mL118.9428 mL
5 mM0.4758 mL2.3789 mL4.7577 mL23.7886 mL
10 mM0.2379 mL1.1894 mL2.3789 mL11.8943 mL
20 mM0.1189 mL0.5947 mL1.1894 mL5.9471 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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Keywords

CW 008
Related Tags: buy CW 008 | purchase CW 008 | CW 008 cost | order CW 008 | CW 008 chemical structure | CW 008 formula | CW 008 molecular weight
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