Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MK-28 is a selective PERK agonist that reduces toxicity and prolongs survival in a Huntington's disease model.MK-28 has a significant killing effect on MK28 gastric cancer cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 100.00 | |
5 mg | In stock | $ 247.00 | |
10 mg | In stock | $ 396.00 | |
25 mg | In stock | $ 766.00 | |
50 mg | In stock | $ 1,160.00 | |
100 mg | In stock | $ 1,730.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 272.00 |
Description | MK-28 is a selective PERK agonist that reduces toxicity and prolongs survival in a Huntington's disease model.MK-28 has a significant killing effect on MK28 gastric cancer cells. |
In vitro | In STHdhQ111/111 cells, MK-28 (0-100 μM; 48 h) rescued cells from ER stress-induced apoptosis[1]. |
In vivo | In R6/2 mice, MK-28 (1 mg/kg; IP, daily for 28 days) increased the survival rate[1]. |
Molecular Weight | 396.44 |
Formula | C24H20N4O2 |
CAS No. | 864388-65-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL (25.22 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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MK-28 864388-65-8 Apoptosis Immunology/Inflammation Antiviral PERK inhibitor inhibit