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Arachidonoyl-N,N-dimethyl amide

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Catalog No. TN11137Cas No. 45280-17-9
Alias Arachidonic acid-N,N-dimethyl amide

Arachidonoyl-N,N-dimethyl amide (Arachidonic acid-N,N-dimethyl amide) is an endogenous cannabinoid that interacts with central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. Its biological activity is terminated through cellular uptake and hydrolysis of the amide bond by fatty acid amide hydrolase. As an analog of arachidonoyl amide, it binds weakly or not at all to human central cannabinoid (CB1) receptors (Ki >1 μM). At a concentration of 50 μM, it can fully inhibit gap junction intercellular communication in rat glial cells.

Arachidonoyl-N,N-dimethyl amide

Arachidonoyl-N,N-dimethyl amide

🥰Excellent
Catalog No. TN11137Alias Arachidonic acid-N,N-dimethyl amideCas No. 45280-17-9
Arachidonoyl-N,N-dimethyl amide (Arachidonic acid-N,N-dimethyl amide) is an endogenous cannabinoid that interacts with central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. Its biological activity is terminated through cellular uptake and hydrolysis of the amide bond by fatty acid amide hydrolase. As an analog of arachidonoyl amide, it binds weakly or not at all to human central cannabinoid (CB1) receptors (Ki >1 μM). At a concentration of 50 μM, it can fully inhibit gap junction intercellular communication in rat glial cells.
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Product Introduction

Bioactivity
Description
Arachidonoyl-N,N-dimethyl amide (Arachidonic acid-N,N-dimethyl amide) is an endogenous cannabinoid that interacts with central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. Its biological activity is terminated through cellular uptake and hydrolysis of the amide bond by fatty acid amide hydrolase. As an analog of arachidonoyl amide, it binds weakly or not at all to human central cannabinoid (CB1) receptors (Ki >1 μM). At a concentration of 50 μM, it can fully inhibit gap junction intercellular communication in rat glial cells.
SynonymsArachidonic acid-N,N-dimethyl amide
Chemical Properties
Molecular WeightC(/C=C\C/C=C\C/C=C\C/C=C\CCCCC)CCC(N(C)C)=O
FormulaC22H37NO
Cas No.45280-17-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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