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5-Bromouridine

Name: 5-Bromouridine
Brand: TargetMol
SKU: T36894
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T36894Cas No. 957-75-5

Alias 5-bromo uridine

5-Bromouridine is a uracil derivative with a broad spectrum of antitumor activity that induces apoptosis in cancer cells by inhibiting DNA synthesis.5-Bromouridine is also used as a marker for DNA and RNA, where the molecule is labeled with a radioisotope or pigment after being introduced into a DNA or RNA strand.

5-Bromouridine

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Purity: 99.89%

Catalog No. T36894Alias 5-bromo uridineCas No. 957-75-5

Pack Size	Price	USA Warehouse	Global Warehouse
200 mg	$30	In Stock	In Stock
500 mg	$41	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$39	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.89%

Appearance:Solid

Color:White

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COA

Product Introduction

Bioactivity

Description	5-Bromouridine is a uracil derivative with a broad spectrum of antitumor activity that induces apoptosis in cancer cells by inhibiting DNA synthesis.5-Bromouridine is also used as a marker for DNA and RNA, where the molecule is labeled with a radioisotope or pigment after being introduced into a DNA or RNA strand.
Synonyms	5-bromo uridine

Chemical Properties

Molecular Weight	323.1
Formula	C₉H₁₁BrN₂O₆
Cas No.	957-75-5
Smiles	O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(=O)C(Br)=C2
Relative Density.	1.9322 g/cm3 (Estimated)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 80 mg/mL (247.6 mM), Sonication is recommended.

PBS (pH 7.2): 2 mg/mL (6.19 mM), Sonication is recommended.

DMSO: 80 mg/mL (247.6 mM), Sonication is recommended.

DMF: 8 mg/mL (24.76 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (10.21 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

PBS (pH 7.2)/DMF/H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0950 mL	15.4751 mL	30.9502 mL	154.7509 mL
5 mM	0.6190 mL	3.0950 mL	6.1900 mL	30.9502 mL

DMF/H2O/DMSO

	1mg	5mg	10mg	50mg
10 mM	0.3095 mL	1.5475 mL	3.0950 mL	15.4751 mL
20 mM	0.1548 mL	0.7738 mL	1.5475 mL	7.7375 mL

H2O/DMSO

	1mg	5mg	10mg	50mg
50 mM	0.0619 mL	0.3095 mL	0.6190 mL	3.0950 mL
100 mM	0.0310 mL	0.1548 mL	0.3095 mL	1.5475 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc