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Glychionide A

🥰Excellent
Catalog No. TN1700Cas No. 119152-50-0

Glychionide A is a flavonoid glycoside discovered in Glycyrrhiza glabra that exhibits antitumor activity against PANC-1 cells by inducing autophagy, apoptosis, cell cycle arrest, and disruption of mitochondrial membrane potential.

Glychionide A

Glychionide A

🥰Excellent
Purity: 99.82%
Catalog No. TN1700Cas No. 119152-50-0
Glychionide A is a flavonoid glycoside discovered in Glycyrrhiza glabra that exhibits antitumor activity against PANC-1 cells by inducing autophagy, apoptosis, cell cycle arrest, and disruption of mitochondrial membrane potential.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$139-In Stock
5 mg$347-In Stock
10 mg$515-In Stock
25 mg$823-In Stock
50 mg$1,090-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.82%
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Product Introduction

Bioactivity
Description
Glychionide A is a flavonoid glycoside discovered in Glycyrrhiza glabra that exhibits antitumor activity against PANC-1 cells by inducing autophagy, apoptosis, cell cycle arrest, and disruption of mitochondrial membrane potential.
In vitro
Glychionide A (3.12-100 μmol/L) significantly inhibited the proliferation of pancreatic carcinoma PANC-1 cells (IC50=14 μmol/L) [1].
Glychionide A (7-28 μmol/L) simultaneously induced autophagy and apoptosis in pancreatic carcinoma cells [1].
Glychionide A (7-28 μmol/L) caused G2/M phase cell cycle arrest in pancreatic carcinoma PANC-1 cells [1].
Glychionide A (7-28 μmol/L) induced ROS production in pancreatic carcinoma PANC-1 cells [1].
Chemical Properties
Molecular Weight446.36
FormulaC21H18O11
Cas No.119152-50-0
SmilesO=C1C=2C(OC(=C1)C3=CC=CC=C3)=C(O)C(O[C@@H]4O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]4O)=CC2O
Relative Density.1.31g/cm3
ColorYellow
AppearanceSolid
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (179.23 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2403 mL11.2017 mL22.4034 mL112.0172 mL
5 mM0.4481 mL2.2403 mL4.4807 mL22.4034 mL
10 mM0.2240 mL1.1202 mL2.2403 mL11.2017 mL
20 mM0.1120 mL0.5601 mL1.1202 mL5.6009 mL
50 mM0.0448 mL0.2240 mL0.4481 mL2.2403 mL
100 mM0.0224 mL0.1120 mL0.2240 mL1.1202 mL

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Keywords

Glychionide A
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