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6-HYDROXYLAMINOURACIL

Name: 6-HYDROXYLAMINOURACIL
Brand: TargetMol
SKU: T9463
Price: 62 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T9463 Copy Product Info

Purity: 99.98%

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6-HYDROXYLAMINOURACIL is a derivative of uracil, which induces DNA damage and apoptosis in tumor cells and inhibits tumor cell growth in vitro.

6-HYDROXYLAMINOURACIL

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Catalog No. T9463

6-HYDROXYLAMINOURACIL is a derivative of uracil, which induces DNA damage and apoptosis in tumor cells and inhibits tumor cell growth in vitro.

Cas No. 20555-88-8

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Pack Size	Price	USA Stock	Global Stock
1 mg	$62	In Stock	In Stock
5 mg	$141	In Stock	In Stock
10 mg	$209	In Stock	In Stock
25 mg	$333	In Stock	In Stock
50 mg	$475	In Stock	In Stock
100 mg	$638	In Stock	In Stock
200 mg	$833	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$100	In Stock	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:99.98%

Appearance:Solid

Color:White

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COA HNMR LCMS

Product Introduction

6-HYDROXYLAMINOURACIL AI Summary

6-HYDROXYLAMINOURACIL shows very low bioactivity, exhibiting a high IC50 value (>100,000.0 nM) for growth inhibition across various human cell lines, including HeLa, MIAPaCa2, SW620, MCF7, and H460, after 72 hours as measured by the MTT assay..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

6-HYDROXYLAMINOURACIL is a derivative of uracil, which induces DNA damage and apoptosis in tumor cells and inhibits tumor cell growth in vitro.

Chemical Properties

Molecular Weight	127.1
Formula	C₄H₅N₃O₂
Cas No.	20555-88-8
Smiles	N(O)=C1NC(=O)NC=C1
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (393.39 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	7.8678 mL	39.3391 mL	78.6782 mL	393.3910 mL
5 mM	1.5736 mL	7.8678 mL	15.7356 mL	78.6782 mL
10 mM	0.7868 mL	3.9339 mL	7.8678 mL	39.3391 mL
20 mM	0.3934 mL	1.9670 mL	3.9339 mL	19.6696 mL
50 mM	0.1574 mL	0.7868 mL	1.5736 mL	7.8678 mL
100 mM	0.0787 mL	0.3934 mL	0.7868 mL	3.9339 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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