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Anti-Mouse ICOS Antibody (7E.17G9) (Synonyms: 7E.17G9)

Catalog No. T9901A-1194 Copy Product Info
Purity: 95%
🥰Excellent
Anti-Mouse ICOS Antibody (7E.17G9) is a mouse anti-ICOS IgG2b monoclonal antibody.Anti-Mouse ICOS Antibody (7E.17G9) upregulates ICOS expression, enhances T cell function, significantly inhibits the immunomodulatory effect of dendritic cells (DCs), and breaks transplantation tolerance.It can be used in the research of inflammatory diseases, cancer and xenotransplantation, such as nephritis and tumors.

Anti-Mouse ICOS Antibody (7E.17G9)

Copy Product Info
🥰Excellent
Catalog No. T9901A-1194
Synonyms 7E.17G9

Anti-Mouse ICOS Antibody (7E.17G9) is a mouse anti-ICOS IgG2b monoclonal antibody.Anti-Mouse ICOS Antibody (7E.17G9) upregulates ICOS expression, enhances T cell function, significantly inhibits the immunomodulatory effect of dendritic cells (DCs), and breaks transplantation tolerance.It can be used in the research of inflammatory diseases, cancer and xenotransplantation, such as nephritis and tumors.

Anti-Mouse ICOS Antibody
(7E.17G9)
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$163InquiryInquiry
5 mg$538InquiryInquiry
10 mgPreferentialInquiryInquiry
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:95%
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Anti-Mouse ICOS Antibody (7E.17G9) is a mouse anti-ICOS IgG2b monoclonal antibody.Anti-Mouse ICOS Antibody (7E.17G9) upregulates ICOS expression, enhances T cell function, significantly inhibits the immunomodulatory effect of dendritic cells (DCs), and breaks transplantation tolerance.It can be used in the research of inflammatory diseases, cancer and xenotransplantation, such as nephritis and tumors.
In vitro
Anti-Mouse ICOS Antibody (7E.17G9) (10 μg/mL, 48 h) significantly inhibits IL-10+ Tregs induced by MPO/BAY dendritic cells (DCs) and suppresses Tregs activation [2].
In vivo
Anti-Mouse ICOS Antibody (7E.17G9) (250–375 μg, i.p., on days 0, 2, 4 and 6) significantly reduced graft tolerance in PD-1 Tg B6 mice with heterotopic abdominal heart transplantation [1].
Anti-Mouse ICOS Antibody (7E.17G9) (0.2 mg, i.p., every other day, from day 13 to day 25) significantly inhibited the induction of IL-10+ Tregs in MPO-immunized C57BL/6 mice [2].
Anti-Mouse ICOS Antibody (7E.17G9) (100 μg, i.p., on days 4, 7 and 10) significantly prolonged survival of C57BL/6 mice bearing KPC tumors and RIP1i [3].
Synonyms7E.17G9
Clone
7E.17G9
Reactivity
Mouse
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetICOS
Chemical Properties
Molecular Weight150 kDa
Antibody Information
IsotypeRat IgG2b kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.

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