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Anti-Mouse ICOS Antibody (7E.17G9)
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Catalog No. T9901A-1194
Alias 7E.17G9
Anti-Mouse ICOS Antibody (7E.17G9) is a mouse anti-ICOS IgG2b monoclonal antibody.Anti-Mouse ICOS Antibody (7E.17G9) upregulates ICOS expression, enhances T cell function, significantly inhibits the immunomodulatory effect of dendritic cells (DCs), and breaks transplantation tolerance.It can be used in the research of inflammatory diseases, cancer and xenotransplantation, such as nephritis and tumors.
Anti-Mouse ICOS Antibody (7E.17G9)
Anti-Mouse ICOS Antibody (7E.17G9)
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Purity: 95%
Catalog No. T9901A-1194Alias 7E.17G9
Anti-Mouse ICOS Antibody (7E.17G9) is a mouse anti-ICOS IgG2b monoclonal antibody.Anti-Mouse ICOS Antibody (7E.17G9) upregulates ICOS expression, enhances T cell function, significantly inhibits the immunomodulatory effect of dendritic cells (DCs), and breaks transplantation tolerance.It can be used in the research of inflammatory diseases, cancer and xenotransplantation, such as nephritis and tumors.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $163 | Inquiry | Inquiry | |
| 5 mg | $538 | Inquiry | Inquiry | |
| 10 mg | Preferential | Inquiry | Inquiry |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:95%
Appearance:Liquid
Color:Transparent
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| Description | Anti-Mouse ICOS Antibody (7E.17G9) is a mouse anti-ICOS IgG2b monoclonal antibody.Anti-Mouse ICOS Antibody (7E.17G9) upregulates ICOS expression, enhances T cell function, significantly inhibits the immunomodulatory effect of dendritic cells (DCs), and breaks transplantation tolerance.It can be used in the research of inflammatory diseases, cancer and xenotransplantation, such as nephritis and tumors. |
| In vitro | Anti-Mouse ICOS Antibody (7E.17G9) (10 μg/mL, 48 h) significantly inhibits IL-10+ Tregs induced by MPO/BAY dendritic cells (DCs) and suppresses Tregs activation [2]. |
| In vivo | Anti-Mouse ICOS Antibody (7E.17G9) (250–375 μg, i.p., on days 0, 2, 4 and 6) significantly reduced graft tolerance in PD-1 Tg B6 mice with heterotopic abdominal heart transplantation [1]. Anti-Mouse ICOS Antibody (7E.17G9) (0.2 mg, i.p., every other day, from day 13 to day 25) significantly inhibited the induction of IL-10+ Tregs in MPO-immunized C57BL/6 mice [2]. Anti-Mouse ICOS Antibody (7E.17G9) (100 μg, i.p., on days 4, 7 and 10) significantly prolonged survival of C57BL/6 mice bearing KPC tumors and RIP1i [3]. |
| Synonyms | 7E.17G9 |
| Clone | 7E.17G9 |
| Reactivity | Mouse |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | ICOS |
| Molecular Weight | 150 kDa |
| Isotype | Rat IgG2b kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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