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CT-2584
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Catalog No. T27094Cas No. 166981-13-1
Alias CT2584, CT 2584
CT-2584 is an anticancer agent that inhibits phospholipid signaling and kills tumor cells through the production of reactive oxygen intermediates. CT-2584 reduces NKEF-B expression in several tumor cell types.
CT-2584 reduced tumor growth in SCID mice by causing shunting of ab initio phospholipid biosynthesis from phosphatidylcholine (PC) to phosphatidylinositol (PI) via PA.
CT-2584
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Purity: 99.77%
Catalog No. T27094Alias CT2584, CT 2584Cas No. 166981-13-1
CT-2584 is an anticancer agent that inhibits phospholipid signaling and kills tumor cells through the production of reactive oxygen intermediates. CT-2584 reduces NKEF-B expression in several tumor cell types.
CT-2584 reduced tumor growth in SCID mice by causing shunting of ab initio phospholipid biosynthesis from phosphatidylcholine (PC) to phosphatidylinositol (PI) via PA.
CT-2584 reduced tumor growth in SCID mice by causing shunting of ab initio phospholipid biosynthesis from phosphatidylcholine (PC) to phosphatidylinositol (PI) via PA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $333 | In Stock | In Stock | |
| 5 mg | $790 | In Stock | In Stock | |
| 10 mg | $1,120 | In Stock | In Stock | |
| 25 mg | $1,670 | In Stock | In Stock | |
| 50 mg | $2,180 | In Stock | In Stock | |
| 100 mg | $2,800 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Purity:99.77%
Appearance:Solid
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | CT-2584 is an anticancer agent that inhibits phospholipid signaling and kills tumor cells through the production of reactive oxygen intermediates. CT-2584 reduces NKEF-B expression in several tumor cell types. CT-2584 reduced tumor growth in SCID mice by causing shunting of ab initio phospholipid biosynthesis from phosphatidylcholine (PC) to phosphatidylinositol (PI) via PA. |
| In vitro | CT-2584 (0-7 μM, 3 days) was toxic to ECV304, to which B/1 cells were highly resistant. [5]；Toxicity was observed in human hepatocellular carcinoma Alex 0 cells at 3.5 mmol/L CT-2584 and Alex 0.5 cells at 2.0 mmol/L CT-2584. 24 hours later, cytotoxicity and decreased HBsAg (hepatitis B surface antigen) secretion were observed, even at lower concentrations. [6] |
| In vivo | Daily intraperitoneal injection of 25 mg/kg CT-2584 for three consecutive days was tolerated in SCID mice. When higher doses (50 mg/kg) were attempted, the animals died due to drug-related peritonitis. [6] |
| Synonyms | CT2584, CT 2584 |
| Molecular Weight | 533.79 |
| Formula | C30H55N5O3 |
| Cas No. | 166981-13-1 |
| Smiles | O=C1C2=C(N=CN2C)N(C(=O)N1CCCCCCCCCC(O)CNCCCCCCCCCCCC)C |
| Relative Density. | 1.31g/cm3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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