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IBI-322 is a bispecific antibody targeting PD-L1 and CD47. In monovalent binding, it can attenuate the activity of CD47, and in bivalent binding, it can block the activity of PD-L1. IBI-322 selectively binds to CD47+PD-L1+ tumor cells, effectively inhibiting the CD47-SIRPα signaling and inducing strong tumor cell phagocytosis in vitro.
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| 1 mg | Inquiry | Inquiry | Inquiry | |
| 5 mg | Inquiry | Inquiry | Inquiry |
| Description | IBI-322 is a bispecific antibody targeting PD-L1 and CD47. In monovalent binding, it can attenuate the activity of CD47, and in bivalent binding, it can block the activity of PD-L1. IBI-322 selectively binds to CD47+PD-L1+ tumor cells, effectively inhibiting the CD47-SIRPα signaling and inducing strong tumor cell phagocytosis in vitro. |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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