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Ecteinascidin 770 inhibits SARS-CoV-2 and Mycobacterium tuberculosis by inhibiting cancer cell viability through RDRP1 (RNA-dependent RNA polymerase 1).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $198 | In Stock | |
5 mg | $493 | In Stock | |
10 mg | $732 | In Stock | |
25 mg | $1,130 | In Stock | |
50 mg | $1,530 | In Stock | |
100 mg | $1,980 | In Stock | |
1 mL x 10 mM (in DMSO) | $689 | In Stock |
Description | Ecteinascidin 770 inhibits SARS-CoV-2 and Mycobacterium tuberculosis by inhibiting cancer cell viability through RDRP1 (RNA-dependent RNA polymerase 1). |
Targets&IC50 | HCT116 cells:0.6 nM, U373MG cells:4.83 nM, DU145 cells:0.81 nM |
In vitro | Methods: U373MG glioblastoma cells were treated with Ecteinascidin 770, and cytotoxicity was detected by MTT assay. Results: The IC 50 value of Ecteinascidin 770 against U373MG cells was 4.83 nM. [1] |
Alias | Et-770, Et770, Ecteinascidine 770 |
Molecular Weight | 770.85 |
Formula | C40H42N4O10S |
Cas No. | 114899-80-8 |
Smiles | C(#N)[C@@H]1N2[C@@]([C@]3(C=4C([C@@]2(COC(=O)[C@@]5(CS3)C=6C(=CC(O)=C(OC)C6)CCN5)[H])=C7C(=C(C)C4OC(C)=O)OCO7)[H])([C@]8(C=9C(C[C@@]1(N8C)[H])=CC(C)=C(OC)C9O)[H])[H] |
Relative Density. | 1.53 g/cm3 (Predicted) |
Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 40 mg/mL (51.89 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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