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Foralumab
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Catalog No. T76748Cas No. 946415-64-1
Alias NI-0401, NI0401
Foralumab (NI-0401) is an orally available human anti-CD3 monoclonal antibody that downregulates NKG7 and increases TGFB1 and GIMAP7 expression in T cells from COVID-19 subjects for the study of COVID-19 infection.
Foralumab
Foralumab
😃Good
Catalog No. T76748Alias NI-0401, NI0401Cas No. 946415-64-1
Foralumab (NI-0401) is an orally available human anti-CD3 monoclonal antibody that downregulates NKG7 and increases TGFB1 and GIMAP7 expression in T cells from COVID-19 subjects for the study of COVID-19 infection.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $169 | In Stock | In Stock | |
| 5 mg | $428 | In Stock | In Stock | |
| 10 mg | $689 | - | In Stock | |
| 25 mg | $1,050 | - | In Stock | |
| 50 mg | $1,420 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:96.7% (SDS-PAGE); 96.4% (SEC-HPLC)
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| Description | Foralumab (NI-0401) is an orally available human anti-CD3 monoclonal antibody that downregulates NKG7 and increases TGFB1 and GIMAP7 expression in T cells from COVID-19 subjects for the study of COVID-19 infection. |
| In vivo | Foralumab (0.6-250 μg; oral; once daily for 5 days) showed delayed rejection in B6Rag2 skin grafts transplanted into humanized mice. [1] Foralumab (0.6-250 μg; oral and inhalation; once daily for 5 days) inhibits rejection of cutaneous xenografts in mice with human immune systems. [1] Foralumab (1-15 μg; oral; once daily for 5 days) demonstrated good bioavailability in humanized mice following intragastric administration. [1] |
| Synonyms | NI-0401, NI0401 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | CD3e |
| Molecular Weight | 146.59 kDa |
| Cas No. | 946415-64-1 |
| Color | Transparent |
| Appearance | Liquid |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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