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Foralumab

(Synonyms: NI-0401, NI0401) Copy Product Info
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Synonyms: NI-0401, NI0401

Catalog No. T76748 Copy Product Info
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Foralumab (NI-0401) is an orally available human anti-CD3 monoclonal antibody that downregulates NKG7 and increases TGFB1 and GIMAP7 expression in T cells from COVID-19 subjects for the study of COVID-19 infection.
Foralumab
Cas No. 946415-64-1
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$169In StockIn Stock
5 mg$428In StockIn Stock
10 mg$689-In Stock
25 mg$1,050-In Stock
50 mg$1,420-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:96.7% (SDS-PAGE); 96.4% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Foralumab (NI-0401) is an orally available human anti-CD3 monoclonal antibody that downregulates NKG7 and increases TGFB1 and GIMAP7 expression in T cells from COVID-19 subjects for the study of COVID-19 infection.
In vivo
Foralumab (0.6-250 μg; oral; once daily for 5 days) showed delayed rejection in B6Rag2 skin grafts transplanted into humanized mice. [1]
Foralumab (0.6-250 μg; oral and inhalation; once daily for 5 days) inhibits rejection of cutaneous xenografts in mice with human immune systems. [1]
Foralumab (1-15 μg; oral; once daily for 5 days) demonstrated good bioavailability in humanized mice following intragastric administration. [1]
SynonymsNI-0401, NI0401
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetCD3e
Chemical Properties
Molecular Weight146.59 kDa
Cas No.946415-64-1
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
StorageStore at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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Related Tags: Foralumab chemical structure | Foralumab in vivo | Foralumab molecular weight