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Foralumab (Synonyms: NI-0401, NI0401)
Catalog No. T76748 Copy Product Info
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Foralumab (NI-0401) is an orally available human anti-CD3 monoclonal antibody that downregulates NKG7 and increases TGFB1 and GIMAP7 expression in T cells from COVID-19 subjects for the study of COVID-19 infection.
Foralumab
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Catalog No. T76748
Synonyms NI-0401, NI0401
Foralumab (NI-0401) is an orally available human anti-CD3 monoclonal antibody that downregulates NKG7 and increases TGFB1 and GIMAP7 expression in T cells from COVID-19 subjects for the study of COVID-19 infection.
Foralumab
Cas No. 946415-64-1
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $169 | In Stock | In Stock | |
| 5 mg | $428 | In Stock | In Stock | |
| 10 mg | $689 | - | In Stock | |
| 25 mg | $1,050 | - | In Stock | |
| 50 mg | $1,420 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:96.7% (SDS-PAGE); 96.4% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Foralumab (NI-0401) is an orally available human anti-CD3 monoclonal antibody that downregulates NKG7 and increases TGFB1 and GIMAP7 expression in T cells from COVID-19 subjects for the study of COVID-19 infection. |
| In vivo | Foralumab (0.6-250 μg; oral; once daily for 5 days) showed delayed rejection in B6Rag2 skin grafts transplanted into humanized mice. [1] Foralumab (0.6-250 μg; oral and inhalation; once daily for 5 days) inhibits rejection of cutaneous xenografts in mice with human immune systems. [1] Foralumab (1-15 μg; oral; once daily for 5 days) demonstrated good bioavailability in humanized mice following intragastric administration. [1] |
| Synonyms | NI-0401, NI0401 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | CD3e |
| Molecular Weight | 146.59 kDa |
| Cas No. | 946415-64-1 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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