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Foralumab
🥰Excellent
Catalog No. T76748Cas No. 946415-64-1
Alias NI-0401, NI0401
Foralumab (NI-0401) is an orally available human anti-CD3 monoclonal antibody that downregulates NKG7 and increases TGFB1 and GIMAP7 expression in T cells from COVID-19 subjects for the study of COVID-19 infection.
Foralumab
Foralumab
🥰Excellent
Purity: 96.7% (SDS-PAGE); 96.4% (SEC-HPLC)
Catalog No. T76748Alias NI-0401, NI0401Cas No. 946415-64-1
Foralumab (NI-0401) is an orally available human anti-CD3 monoclonal antibody that downregulates NKG7 and increases TGFB1 and GIMAP7 expression in T cells from COVID-19 subjects for the study of COVID-19 infection.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $169 | In Stock | |
| 5 mg | $428 | In Stock | |
| 10 mg | $689 | In Stock | |
| 25 mg | $1,050 | In Stock | |
| 50 mg | $1,420 | In Stock |
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Concentration:5.39 mg/mL
Purity:96.7% (SDS-PAGE); 96.4% (SEC-HPLC)
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Product Introduction
Bioactivity
Chemical Properties
| Description | Foralumab (NI-0401) is an orally available human anti-CD3 monoclonal antibody that downregulates NKG7 and increases TGFB1 and GIMAP7 expression in T cells from COVID-19 subjects for the study of COVID-19 infection. |
| In vivo | Foralumab (0.6-250 μg; oral; once daily for 5 days) showed delayed rejection in B6Rag2 skin grafts transplanted into humanized mice. [1] Foralumab (0.6-250 μg; oral and inhalation; once daily for 5 days) inhibits rejection of cutaneous xenografts in mice with human immune systems. [1] Foralumab (1-15 μg; oral; once daily for 5 days) demonstrated good bioavailability in humanized mice following intragastric administration. [1] |
| Synonyms | NI-0401, NI0401 |
| Cas No. | 946415-64-1 |
| Color | Transparent |
| Appearance | Liquid |
Storage & Solubility Information
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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