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HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (His)

(Synonyms: RASK2, RALD, NS3, NS, MHC, K-RAS4B, K-RAS4A, K-RAS2B, K-RAS2A, KRAS2, KRAS1, K-Ras 2, KRAS, KI-RAS, GTPase Kras, C-K-RAS, CFC2) Copy Product Info

Synonyms: RASK2, RALD, NS3, NS, MHC, K-RAS4B, K-RAS4A, K-RAS2B, K-RAS2A, KRAS2, KRAS1, K-Ras 2, KRAS, KI-RAS, GTPase Kras, C-K-RAS, CFC2

Catalog No. TMPK-01870 Copy Product Info
HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (His) is expressed in HEK293 Cells. The accession number is AAV53343.1(HLA-A*11:01)&P61769(B2M)&VVVGADGVGK.
HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (His)
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Pack SizePriceUSA StockGlobal StockQuantity
10 µg$1137-10 days7-10 days
20 µg$1757-10 days7-10 days
50 µg$3167-10 days7-10 days
100 µg$4907-10 days7-10 days
200 µg$7937-10 days7-10 days
500 µg$1,4707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Immobilized HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) TCR at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Human HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer, His Tag with the EC50 of 59.4 ng/ml determined by ELISA (QC Test).
Description
HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (His) is expressed in HEK293 Cells. The accession number is AAV53343.1(HLA-A*11:01)&P61769(B2M)&VVVGADGVGK.
Species
Human
Expression System
HEK293 Cells
TagC-His
Accession NumberAAV53343.1(HLA-A*11:01)&P61769(B2M)&VVVGADGVGK
ConstructionGly25-Thr305 (HLA-A*11:01), Ile21-Met119 (B2M) and VVVGADGVGK peptide
Protein Purity
> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Endotoxin< 1 EU/μg of the protein as determined by the LAL method.
FormulationSupplied as 0.22 μm filtered solution in PBS (pH 7.4).
SynonymsRASK2, RALD, NS3, NS, MHC, K-RAS4B, K-RAS4A, K-RAS2B, K-RAS2A, KRAS2, KRAS1, K-Ras 2, KRAS, KI-RAS, GTPase Kras, C-K-RAS, CFC2
Research Background
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
Chemical Properties
Molecular Weight48.40 kDa (Predicted); 50-60 kDa (Reducing condition, due to glycosylation)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (His) chemical structure | HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (His) molecular weight