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2,4,6-Trihydroxybenzaldehyde

Name: 2,4,6-Trihydroxybenzaldehyde
Brand: TargetMol
SKU: TN1206
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN1206Cas No. 487-70-7

2,4,6-Trihydroxybenzaldehyde is a natural product. 2,4,6-Trihydroxybenzaldehyde, a potential anti-obesity treatment, suppressed adipocyte differentiation in 3T3-L1 cells and fat accumulation induced by high-fat diet in C57BL/6 mice. It is also a potent antidiabetic agent. 2,4,6-Trihydroxybenzaldehyde has potential anticancer activity.

2,4,6-Trihydroxybenzaldehyde

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Purity: 97.29%

Catalog No. TN1206Cas No. 487-70-7

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
200 mg	$29	-	In Stock
1 mL x 10 mM (in DMSO)	$35	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:97.29%

Appearance:Solid

Color:Yellow

Resource Download

COA HPLC HNMR LCMS

Product Introduction

2,4,6-Trihydroxybenzaldehyde AI Summary

2,4,6-Trihydroxybenzaldehyde exhibits antidiabetic and antihyperglycemic activities by reducing blood glucose levels in both streptozotocin-induced diabetic rat models and glucose-treated rats. It also demonstrates significant antioxidant activity, as evidenced by its ability to scavenge DPPH free radicals with a high activity of 91.2% and moderate hydroxyl radical scavenging activities of 42.0% and 36.0%. In terms of enzymatic inhibition, 2,4,6-Trihydroxybenzaldehyde inhibits alpha-glucosidase with an IC50 of 4600.0 nM. Additionally, it inhibits the nucleation phase of HFIP-treated 15N-labelled wild type Amyloid beta (1-42) in a Thioflavin-T fluorescence assay, taking 3.0 hours at a concentration of 50 µM in the presence of fibril seed, suggesting potential in amyloid-related research..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

Chemical Properties

Molecular Weight	154.12
Formula	C₇H₆O₄
Cas No.	487-70-7
Smiles	OC1=CC(O)=C(C=O)C(O)=C1
Relative Density.	1.3725 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (324.42 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (12.98 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.4885 mL	32.4423 mL	64.8845 mL	324.4225 mL
5 mM	1.2977 mL	6.4885 mL	12.9769 mL	64.8845 mL
10 mM	0.6488 mL	3.2442 mL	6.4885 mL	32.4423 mL
20 mM	0.3244 mL	1.6221 mL	3.2442 mL	16.2211 mL
50 mM	0.1298 mL	0.6488 mL	1.2977 mL	6.4885 mL
100 mM	0.0649 mL	0.3244 mL	0.6488 mL	3.2442 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc