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NSC49652

🥰Excellent
Catalog No. T28206Cas No. 908563-68-8
Alias NSC-49652, NSC 49652

NSC49652 triggers apoptotic cell death dependent on p75NTR and JNK activity in neurons and melanoma cells, and inhibits tumor growth in a melanoma mouse model.

NSC49652

NSC49652

🥰Excellent
Purity: 98.98%
Catalog No. T28206Alias NSC-49652, NSC 49652Cas No. 908563-68-8
NSC49652 triggers apoptotic cell death dependent on p75NTR and JNK activity in neurons and melanoma cells, and inhibits tumor growth in a melanoma mouse model.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$31In StockIn Stock
5 mg$72In StockIn Stock
10 mg$122In StockIn Stock
25 mg$247In StockIn Stock
50 mg$392In StockIn Stock
100 mg$589In StockIn Stock
500 mg$1,280-In Stock
1 mL x 10 mM (in DMSO)$79In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.98%
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Product Introduction

Bioactivity
Description
NSC49652 triggers apoptotic cell death dependent on p75NTR and JNK activity in neurons and melanoma cells, and inhibits tumor growth in a melanoma mouse model.
SynonymsNSC-49652, NSC 49652
Chemical Properties
Molecular Weight225.24
FormulaC14H11NO2
Cas No.908563-68-8
SmilesOc1ccccc1C(=O)\C=C\c1cccnc1
Relative Density.1.241 g/cm3 (Predicted)
ColorYellow
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (221.99 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.4397 mL22.1985 mL44.3971 mL221.9854 mL
5 mM0.8879 mL4.4397 mL8.8794 mL44.3971 mL
10 mM0.4440 mL2.2199 mL4.4397 mL22.1985 mL
20 mM0.2220 mL1.1099 mL2.2199 mL11.0993 mL
50 mM0.0888 mL0.4440 mL0.8879 mL4.4397 mL
100 mM0.0444 mL0.2220 mL0.4440 mL2.2199 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

NSC49652Apoptosis
Related Tags: buy NSC49652 | purchase NSC49652 | NSC49652 cost | order NSC49652 | NSC49652 chemical structure | NSC49652 formula | NSC49652 molecular weight
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