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NSC49652

Name: NSC49652
Brand: TargetMol
SKU: T28206
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T28206Cas No. 908563-68-8

Alias NSC-49652, NSC 49652

NSC49652 triggers apoptotic cell death dependent on p75NTR and JNK activity in neurons and melanoma cells, and inhibits tumor growth in a melanoma mouse model.

NSC49652

🥰Excellent

Purity: 98.98%

Catalog No. T28206Alias NSC-49652, NSC 49652Cas No. 908563-68-8

NSC49652 triggers apoptotic cell death dependent on p75NTR and JNK activity in neurons and melanoma cells, and inhibits tumor growth in a melanoma mouse model.

Pack Size	Price	Availability
1 mg	$31	In Stock
5 mg	$72	In Stock
10 mg	$122	In Stock
25 mg	$247	In Stock
50 mg	$392	In Stock
100 mg	$589	In Stock
500 mg	$1,280	In Stock
1 mL x 10 mM (in DMSO)	$79	In Stock

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Batch Information

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Purity:98.98%

Resource Download

COA HNMR HPLC LCMS

Product Introduction

Bioactivity

Description	NSC49652 triggers apoptotic cell death dependent on p75NTR and JNK activity in neurons and melanoma cells, and inhibits tumor growth in a melanoma mouse model.
Synonyms	NSC-49652, NSC 49652

Chemical Properties

Molecular Weight	225.24
Formula	C₁₄H₁₁NO₂
Cas No.	908563-68-8
Smiles	Oc1ccccc1C(=O)\C=C\c1cccnc1
Relative Density.	1.241 g/cm3 (Predicted)
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (221.99 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.4397 mL	22.1985 mL	44.3971 mL	221.9854 mL
5 mM	0.8879 mL	4.4397 mL	8.8794 mL	44.3971 mL
10 mM	0.4440 mL	2.2199 mL	4.4397 mL	22.1985 mL
20 mM	0.2220 mL	1.1099 mL	2.2199 mL	11.0993 mL
50 mM	0.0888 mL	0.4440 mL	0.8879 mL	4.4397 mL
100 mM	0.0444 mL	0.2220 mL	0.4440 mL	2.2199 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc